21 citations
,
January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
21 citations
,
September 2019 in “Archives of Physiology and Biochemistry” High-intensity interval training improves certain hormone levels and lipid profiles in women with PCOS.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
9 citations
,
January 1997 in “Endocrine Journal” Gonadal biopsy is the best method to diagnose gonadal dysgenesis.
research Acne
4 citations
,
January 2019 Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.
June 2024 in “Clinical Endocrinology and Metabolism” Balancing hormones is crucial for women's health and may require hormone therapy.
August 2023 in “Clinical Endocrinology and Metabolism” Balancing hormones can help women feel youthful and healthy.
January 2017 in “Qucosa (Saxon State and University Library Dresden)” Plasma protein binding significantly affects glucocorticosteroid concentration in blood, saliva, and hair.
January 2015 in “Indian Journal of Medical Biochemistry” Men with early balding should be checked for metabolic syndrome, as there's a link between the two.
129 citations
,
January 2019 in “Clinical medicine insights” Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.
September 2012 in “The Egyptian Journal of Histology” Flutamide caused damage to male rat reproductive organs and may affect fertility.
59 citations
,
October 2020 in “Stem Cell Reviews and Reports” Men have higher COVID-19 mortality rates than women due to biological and lifestyle factors.
June 2025 in “Journal of Endocrinological Investigation” Adrenal disorders often cause high blood pressure in young people.
166 citations
,
March 2007 in “Hypertension” High androgen levels in young women with PCOS are linked to higher blood pressure.
117 citations
,
May 2017 in “Human Reproduction Update” The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
71 citations
,
June 2006 in “Human Reproduction” Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.
65 citations
,
May 2010 in “Current Women's Health Reviews” Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.
49 citations
,
July 2021 in “Nutrients” Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.
40 citations
,
February 2005 in “Fertility and Sterility” Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.
32 citations
,
September 2018 in “Clinical Obstetrics and Gynecology” Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
29 citations
,
July 2013 in “The Journal of Sexual Medicine” Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
28 citations
,
August 2009 in “Nursing for Women's Health” Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.
25 citations
,
October 2019 in “Journal of Endocrinological Investigation” Both types of oral contraceptives improved symptoms and hormone levels in women with PCOS.
20 citations
,
December 2000 in “Fertility and Sterility” The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.
15 citations
,
January 2015 in “Clinical and Experimental Reproductive Medicine” Taiwanese women with PCOS experience different symptoms based on age, with younger women facing more hormone imbalances and older women dealing with more metabolic issues.
14 citations
,
September 2017 in “Clinics in Dermatology” Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.
12 citations
,
March 2015 in “Pediatric Dermatology” Early diagnosis and treatment of PCOS in young people is important to prevent long-term health problems.
3 citations
,
March 2018 in “Journal of Continuing Education in Nursing” Continuing education programs significantly increased rural nurse practitioners' knowledge about PCOS.
2 citations
,
December 2022 in “International Journal of Infertility & Fetal Medicine” Obese and lean women with PCOS have different symptoms and need different treatments.
1 citations
,
February 2025 in “Frontiers in Medicine” JSLE patients often have more hormone and metabolism issues, so regular check-ups and preventing obesity can help.