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research Sex differences in SARS-CoV-2 infection rates and the potential link to prostate cancer

113 citations , July 2020 in “Communications biology”

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

research Impaired turnover of autophagolysosomes in cathepsin L deficiency

113 citations , June 2010 in “Biological Chemistry”

Cathepsin L deficiency causes large, abnormal cell structures and health issues in mice.

research Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models.

112 citations , January 2004 in “The International journal of developmental biology”

Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.

research Impaired Notch‐MKP‐1 signalling in hidradenitis suppurativa: an approach to pathogenesis by evidence from translational biology

112 citations , January 2013 in “Experimental dermatology”

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase

research 2-Substituted 4-(Thio)chromenone 6-Oi>-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase

111 citations , August 2002 in “Journal of Medicinal Chemistry”

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

research Disorders linked to insufficient androgen action in male children
111 citations , May 2001 in “Human reproduction update”

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

research Efficacy of interventions for prevention of chemotherapy‐induced alopecia: A systematic review and meta‐analysis
110 citations , August 2014 in “International journal of cancer”

Scalp cooling significantly reduces chemotherapy-induced hair loss.

research Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth.
109 citations , July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

research The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer
108 citations , February 2008 in “The Journal of urology/The journal of urology”

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

research Neurogenic Inflammation in Stress-Induced Termination of Murine Hair Growth Is Promoted by Nerve Growth Factor
108 citations , July 2004 in “American Journal of Pathology”

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

research A pilot study of ICG laser therapy of acne vulgarisi>: Photodynamic and photothermolysis treatment
108 citations , December 2003 in “Lasers in surgery and medicine”

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

research From skin microrelief to wrinkles. An area ripe for investigation
108 citations , January 2003 in “Journal of Cosmetic Dermatology”

Wrinkles form due to structural skin changes and vary in type and treatment response.

research Androgen receptor–mediated inhibition of cutaneous wound healing
108 citations , September 2002 in “The Journal of clinical investigation/The journal of clinical investigation”

Lowering testosterone speeds up wound healing in male mice.

research Extrapulmonary disorders associated with Rhodococcus equi infection in foals: 150 cases (1987–2007)
108 citations , October 2009 in “Javma-journal of The American Veterinary Medical Association”

Foals with Rhodococcus equi infection often have other health problems that lower their chances of survival.

research Interferon in the treatment of cutaneous T-cell lymphoma
107 citations , December 2003 in “Dermatologic Therapy”

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

research Artificial intelligence: revolutionizing robotic surgery: review
106 citations , August 2024 in “Annals of Medicine and Surgery”

AI in robotic surgery improves precision and safety but faces cost and ethical challenges.

research Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31
106 citations , March 2013 in “Nature Communications”

A new genetic region, 17q21.31, is linked to higher ovarian cancer risk.

research Immunological challenges associated with artificial skin grafts: available solutions and stem cells in future design of synthetic skin
105 citations , December 2017 in “Journal of Biological Engineering”

Artificial skin grafts face immune rejection, but stem cells may improve future designs.

research Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth
105 citations , May 2011 in “The journal of investigative dermatology/Journal of investigative dermatology”

Activating TRPV3 stops human hair growth.

research Treatment of Obstructive Sleep Apnea Improves Cardiometabolic Function in Young Obese Women with Polycystic Ovary Syndrome
105 citations , February 2011 in “The Journal of Clinical Endocrinology & Metabolism”

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

research Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
105 citations , August 2010 in “Pharmacology & therapeutics”

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

research Thyroid-Stimulating Hormone, a Novel, Locally Produced Modulator of Human Epidermal Functions, Is Regulated by Thyrotropin-Releasing Hormone and Thyroid Hormones
105 citations , February 2010 in “Endocrinology”

The skin produces and responds to thyroid-stimulating hormone, which is controlled by other thyroid-related hormones.

research Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study
104 citations , March 2014 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

DHT may increase the risk of heart disease and death in elderly men.

research Psoriasis treatment in difficult locations: scalp, nails, and intertriginous areas
104 citations , August 2008 in “Clinics in Dermatology”

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

research Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss
104 citations , January 2023 in “Journal of Clinical Medicine”

A holistic approach is needed to effectively address hair loss by understanding and influencing the hair growth cycle.

research Hyperandrogenism and insulin resistance modulate gravid uterine and placental ferroptosis in PCOS-like rats
104 citations , June 2020 in “Journal of Endocrinology”

Hyperandrogenism and insulin resistance in PCOS-like rats can lead to pregnancy complications due to increased cell death in the uterus and placenta.

research Recent advances in understanding and managing male infertility
104 citations , May 2019 in “F1000Research”

Losing weight, fixing varicoceles, and using advanced sperm selection methods improve male infertility treatment outcomes.

research A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females
103 citations , March 2015 in “Nature Communications”

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

research In vivo immunological toxicity in mice of carbon nanotubes with impurities
103 citations , January 2009 in “Carbon”

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

research Influence of prostaglandin F_2α and its analogues on hair regrowth and follicular melanogenesis in a murine model
103 citations , April 2005 in “Experimental dermatology”

Prostaglandin F2alpha and related compounds can increase hair growth and darken hair in mice.

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