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New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Sex hormones affect dog skin conditions, but more data is needed.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Hirsutism involves excessive hair growth due to hormonal issues and can be treated with medication or surgery.

Accurate diagnosis of hyperandrogenism, especially PCOS, is crucial for managing fertility and metabolic risks in women.

A golden lion tamarin had Cushing's disease due to a pituitary tumor, leading to its euthanasia.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Dermatologists are crucial in providing personalized care for patients with sex development differences.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

The document is a detailed medical reference on skin and genetic disorders.

Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.

Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.

High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.

An 84-year-old woman's hair loss was due to a rare condition called Leydig cell hyperplasia, which was treated with surgery.

A dog's skin calcification condition resolved without treatment after a bacterial infection.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Tetracycline successfully treated a Labrador's skin calcification and hair loss.

A woman's excessive hair growth and masculine features were due to a rare benign ovarian tumor and endometrial cancer, which improved after surgery.

A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.

A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

ChatGPT-5 can pass the endocrinology exam but isn't fully reliable for clinical decisions yet.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.

Environmental, chemical, mechanical, and personal health factors can all damage hair and contribute to hair loss or changes in hair quality.

Untreated congenital adrenal hyperplasia can lead to complications like stroke and needs glucocorticoid treatment.

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

A PET-CT scan successfully located a hard-to-find Leydig cell tumor in a woman with hormonal symptoms.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.