January 2016 in “Archivio italiano di urologia, andrologia” The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
122 citations
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July 1990 in “Teratology” Finasteride exposure in pregnancy causes genital abnormalities in male rats.
1 citations
,
August 2015 in “Current Sexual Health Reports” 5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
May 2018 in “Reactions Weekly” Finasteride treatment for hair loss can cause erectile dysfunction.
2 citations
,
October 2017 in “Drug safety - case reports” Finasteride for hair loss may cause painless bleeding in urine and semen.
October 2024 in “Andrology” Paternal drug exposure can harm fertility, pregnancy outcomes, and offspring health, with specific drugs linked to various reproductive issues.
April 2017 in “The Journal of urology/The journal of urology” Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.
October 1999 in “The Journal of Urology” New treatments and diagnostic methods for urological conditions show promise, but some lack sufficient accuracy for clinical use.
January 2020 in “Fertility and Sterility” The conclusion is that it's currently unclear if certain rare medical conditions are caused by specific factors due to mostly observational data.
August 2012 in “Pharmaceutical Medicine” The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
Long-term finasteride use may affect sperm structure and chromosomes.
January 2023 in “Andrologia” American men are older, more obese, and have longer infertility than Canadian men.
February 2024 in “Urology” Certain medications, especially Paroxetine, Tamsulosin, and Finasteride, are linked to ejaculatory disorders.
April 2025 in “The Journal of Urology” Long-term finasteride use may lower prostate cancer risk but increase the need for erectile dysfunction medication.
2 citations
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October 1999 in “The Journal of Urology”
October 2010 in “Journal of Men's Health” Larger prostate size in older men may be linked to poorer semen quality and fertility issues.
241 citations
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March 2000 in “The Journal of Urology” Men over 50 may experience hormone decline causing various symptoms, and proper management is crucial.
1 citations
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October 2022 in “Springer eBooks” Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.
Finasteride causes reproductive malformations in male rats.
May 2024 in “The journal of sexual medicine” Finasteride treatment may cause erectile dysfunction, but stopping it reverses these effects.
7 citations
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September 1997 in “PubMed” 1 citations
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January 2015 in “Elsevier eBooks” Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.
June 2025 in “JCEM Case Reports” False high testosterone levels were corrected using a more accurate test.
78 citations
,
December 2008 in “The Journal of Sexual Medicine” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction, but the exact reasons are unclear.
20 citations
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January 2007 in “Fertility and Sterility” A woman developed male traits from accidental contact with her husband's testosterone gel.
July 2021 in “Reactions Weekly” Man experienced lasting sexual dysfunction from finasteride, but malpractice claim was rejected.
1 citations
,
February 2018 in “The Journal of Sexual Medicine” Ultrasound shows 96% of young men with erectile dysfunction after using finasteride have abnormal penile tissue.