190 citations
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October 2002 in “The FASEB journal” Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
175 citations
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December 2014 in “PLoS Biology” Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.
159 citations
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December 2007 in “American Journal of Pathology” Stress-related substance P may lead to hair loss and negatively affect hair growth.
116 citations
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September 2020 in “Nature Communications” The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
108 citations
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September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Lowering testosterone speeds up wound healing in male mice.
105 citations
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February 1996 in “Journal of biological chemistry/The Journal of biological chemistry” The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
101 citations
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November 2011 in “Nature Communications” Wnt/β-catenin signaling is crucial for cell fusion in placental development.
97 citations
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March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
91 citations
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March 2011 in “Stem Cell Reviews and Reports” Human epidermal neural crest stem cells can become bone and skin pigment cells, making them useful for therapies.
91 citations
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May 2005 in “The Journal of Clinical Endocrinology & Metabolism” A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
71 citations
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October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” HFMs can help study hair growth and test potential hair growth drugs.
68 citations
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March 2008 in “Experimental dermatology” The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
62 citations
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November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
58 citations
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June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.
57 citations
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June 2003 in “American Journal of Physiology-cell Physiology” Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
57 citations
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April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D receptor is crucial for starting hair growth after birth.
56 citations
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September 2013 in “Journal of Biochemistry and Molecular Biology” Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
53 citations
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January 2011 in “Diabetes” People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
49 citations
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October 2009 in “Cancer research” Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
45 citations
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July 2002 in “The Neurologist” A comprehensive approach to educating patients and managing side effects is crucial for improving adherence to multiple sclerosis treatments and patient quality of life.
44 citations
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October 2017 in “Scientific Reports” Far-infrared radiation improves stem cell growth and movement, helping heart therapy.
34 citations
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April 2009 in “Skin Pharmacology and Physiology” Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
32 citations
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May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
32 citations
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August 2015 in “Journal of Investigative Dermatology” Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
32 citations
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January 2007 in “Biological & Pharmaceutical Bulletin” Minoxidil and retinol together help hair grow.
28 citations
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May 2019 in “Life Sciences” Ginsenoside Rb1 from Panax ginseng helps mink hair grow by activating certain cell signals.
27 citations
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April 2018 in “Scientific Reports” Psoriasis patients' immune response to a hair protein depends on their specific gene type.
26 citations
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August 2019 in “Stem Cell Research & Therapy” PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
25 citations
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November 2017 in “Molecular Medicine Reports” PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.
24 citations
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January 2016 in “Lasers in Medical Science” Erbium glass laser treatment may help with skin remodeling, reduce inflammation, and improve skin cell maturation.