April 2019 in “Journal of the Endocrine Society” A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.
3 citations
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April 2012 in “Cancer research” Mouse skin cancer progression involves a unique group of cells marked by ABCG2 and MTS24.
13 citations
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January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
February 2014 in “PubMed” Modified rat hair follicle stem cells can help create artificial hair follicles, blood vessels, and skin.
76 citations
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February 2007 in “Cancer Research” Protein Kinase Cε increases skin sensitivity to UV damage and skin cancer risk.
September 2023 in “Journal of the American Academy of Dermatology” 8 citations
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December 2017 in “Small Ruminant Research” Variation in the TCHH gene affects wool curliness in sheep.
6 citations
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November 2023 in “Clinical Pharmacokinetics” Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.
16 citations
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March 2013 in “The Journal of Dermatology” Low TRPS1 expression in skin and hair cells is linked to hair problems in Trichorhinophalangeal syndrome.
16 citations
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August 2021 in “Tumor Biology” TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.
2 citations
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January 2014 in “Photochemical & photobiological sciences” Grasp protein helps maintain skin health after UVB exposure.
1 citations
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December 2024 in “The Journal of Dermatology” The study developed mouse models to help research and treat hair and sweat gland issues.
7 citations
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March 1931 in “Experimental Biology and Medicine” Iron deficiency causes hair loss in white rats and mice.
11 citations
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January 2017 in “Biochemical and biophysical research communications” 1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.
May 2010 in “Europe PMC (PubMed Central)” Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.
September 2019 in “Journal of Investigative Dermatology” Researchers successfully used nude mice to study human hair growth, which could help with future hair research.
February 2025 in “International Journal of Molecular Sciences” RIPK1 inhibitors may help prevent alopecia areata by reducing immune cell activity.
2 citations
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May 2023 in “The Journal of Immunology” NXC736 significantly reduced hair loss in mice with alopecia areata.
27 citations
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December 1997 in “Archives of Dermatological Research” Rat dermal papilla cells have unique properties and interact differently with their environment compared to other skin cells.
2 citations
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January 2001 in “Biomedical Research” Trichohyalin and peptidylarginine deiminase type III are found together in rat hair follicles, with trichohyalin being modified after expression.
163 citations
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October 2001 in “EMBO journal” Overexpressing follistatin in mice delays wound healing and reduces scar size.
16 citations
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April 2024 in “Proceedings of the National Academy of Sciences” HDAC4 and HDAC7 are crucial for Th17 cell development and could be targeted to treat inflammatory diseases.
January 2025 in “SSRN Electronic Journal” 14 citations
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April 2016 in “PloS one” The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.
4 citations
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July 1987 in “Laboratory Animals” Female rats aged 8 weeks are best for this model.
51 citations
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August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
1 citations
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December 2022 in “Animals” Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.
7 citations
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December 2008 in “Journal of Dermatological Science” Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.
40 citations
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July 2008 in “PROTEOMICS” A new model helps study acne and test treatments.
8 citations
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September 2011 in “Scanning” Multiphoton microscopy effectively images mouse skin layers and structures.