June 2020 in “AACE clinical case reports” A woman's severe male hormone excess was caused by a small, hard-to-find ovarian tumor.
November 2022 in “Journal of the Endocrine Society” A 21-year-old male with a rare genetic disorder experienced sudden hair loss and high DHEAS levels, likely due to a condition similar to PCOS, usually seen in women.
4 citations
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May 2019 in “Reproductive Endocrinology” Accurate diagnosis of hyperandrogenism, especially PCOS, is crucial for managing fertility and metabolic risks in women.
October 2024 in “Journal of the Endocrine Society” Leydig cell tumors can cause high testosterone and symptoms in postmenopausal women, and removing them improves symptoms.
1 citations
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January 2018 in “Journal of Gynecologic Surgery” Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.
October 2024 in “Journal of the Endocrine Society” Ovarian stromal hyperplasia can cause high testosterone in postmenopausal women and is treated by removing the ovaries.
December 2023 in “Expert Review of Endocrinology & Metabolism” New methods help diagnose skin conditions caused by too much male hormone in women, like acne, hair loss, and excess hair growth.
September 2021 in “Conference Proceedings” Older men with high total testosterone might not show symptoms, while younger men with hyperandrogenism may experience hair loss or acne.
1 citations
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July 2015 in “AACE clinical case reports” Removing both ovaries treated the woman's excess male hormone symptoms.
April 2019 in “Journal of the Endocrine Society” Bilateral ovarian hyperthecosis is a rare but treatable cause of increased facial hair in postmenopausal women.
11 citations
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September 1990 in “Clinical Endocrinology” Girls with prepubertal simple hypertrichosis have higher dihydrotestosterone (DHT) levels.
63 citations
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March 2011 in “Clinical Endocrinology” Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.
April 2019 in “Journal of the Endocrine Society” A woman's severe male-like symptoms were caused by a rare, benign tumor in her ovary that produced male hormones.
April 2020 in “Journal of the Endocrine Society” A rare ovarian tumor caused high male hormone levels, but surgery fixed it.
7 citations
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January 2015 in “Case reports in endocrinology” The document concludes that HAIR-AN syndrome should be considered when a patient shows severe hyperandrogenism and insulin resistance after excluding tumors.
January 1983 in “Elsevier eBooks” Masculinization in affected individuals occurs gradually after puberty due to hormone changes.
July 2024 in “Journal of Pediatric Endocrinology and Metabolism” Ovarian hyperthecosis should be considered in young women with severe male-like symptoms and can be managed with hormone treatments.
October 2024 in “Journal of the Endocrine Society” The case highlights the complexity of diagnosing high testosterone in older women and the need for thorough testing.
January 2013 in “Revista Clínica Española” A postmenopausal woman's increased male hormone levels were successfully treated with surgery.
7 citations
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January 2011 in “Journal of The American Academy of Dermatology” Most women with hyperandrogenism first show acne, and skin conditions like hirsutism and acanthosis nigricans are good indicators of the condition.
October 2024 in “Journal of the Endocrine Society” Bilateral salpingo-oophorectomy resolved hyperandrogenism in a postmenopausal woman with rare ovarian tumors.
46 citations
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December 1992 in “The Journal of Steroid Biochemistry and Molecular Biology” Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.
October 2024 in “Journal of the Endocrine Society” Leydig cell tumors can cause high testosterone and symptoms like hair loss in postmenopausal women, but surgery can improve these symptoms.
March 1997 in “The Lancet” Hirsutism is abnormal male-pattern hair growth in females due to excess androgens.
January 2026 in “Brazilian Journal of Development” Early diagnosis and surgery can improve symptoms of ovarian hyperthecosis in postmenopausal women.
October 2023 in “Journal of the Endocrine Society” The document concludes that doctors should thoroughly check postmenopausal women with sudden increased male traits for rare conditions like androgen-producing endometrial cancer.
2 citations
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October 2015 in “Obstetrics and gynaecology cases - reviews” Removing both ovaries may better treat increased male hormone levels and related symptoms in postmenopausal women when hormone therapy doesn't work.
3 citations
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January 2017 in “Gynecological endocrinology” A postmenopausal woman's excess male hormone symptoms were caused by a rare adrenal gland tissue in her ovary.
1 citations
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November 2002 in “Endocrine practice” The patient's high testosterone was reduced by a medication that suppresses gonadotropin.
April 2020 in “Journal of the Endocrine Society” A woman's high testosterone and related symptoms were caused by overactive cells in her ovaries.