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Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

Innovative methods are reducing animal testing and improving biomedical research.

Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.

Low testosterone can cause a heart rhythm problem in men, but fixing it can prevent the issue.

New compounds may help treat heart disease by activating specific potassium channels.

QLT0267 stops hair follicle cell growth and movement.

Keratin K6irs is a marker for the inner root sheath of hair follicles in mice and humans.

The inhibitor affects androgen metabolism but not ovarian function.

BKN-1 antibody targets specific keratin in basal cell epithelioma and normal skin basal cells.

K25, K27, and K28 are found in all inner root sheath layers of hair, while K26 is only in the cuticle.

TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.

Deleting Crif1 in mouse skin disrupts skin balance and hair growth.

The STRIPAK complex is crucial for skin cell organization and creating a functional skin barrier.

Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.

Four specific keratins in hair follicles help understand hair structure and function.

Potassium channel modulators mostly increase the activity of rat whisker mechanoreceptors.

Ixekizumab helps improve life quality, physical ability, and work performance in patients with psoriatic arthritis who haven't used biologic drugs before.

Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.

NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.

A new protein, mK6irs, is found in specific hair layers and may help understand hair growth and diseases.

Topical IKKα inhibitors may help prevent CCS tumours.

Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.

A rare genetic deletion in the KRT1 gene causes unique skin symptoms in a family.

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.

Long-term data and a team approach are needed to manage chronic side effects from cancer treatments.

Abrocitinib at 100 mg and 200 mg daily may significantly improve moderate-to-severe atopic dermatitis in patients 12 years and older.