research Pharma maker recalls drug over undeclared anti-hypertensive drug
A medicine company has recalled a drug because it contained an unlisted blood pressure medication.
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research In vivo evaluation of the efficacy, toxicity and biodistribution of PLGA-DMSA nanoparticles loaded with itraconazole for treatment of paracoccidioidomycosis
Itraconazole-loaded nanoparticles are more effective and less toxic for treating fungal infections than conventional oral itraconazole.
research Nonsurgical Facial Esthetic Procedures
Nonsurgical facial treatments are becoming more popular due to their natural-looking results and minimal invasiveness.
research Medical consequences of long-term anabolic-androgenic Steroids (AASs) abuses in athletes
Long-term steroid abuse in athletes causes serious health risks, outweighing any benefits.
research In adults with alopecia areata, are topical corticosteroids as effective as intralesional injections in promoting hair regrowth?
Intralesional corticosteroids work better than topical ones for hair regrowth in alopecia areata.
research Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone.
GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
research Sexual Medicine Reviews—The Premiere Review Journal for the Field of Sexual Medicine
Current treatments for recurrent ischemic priapism are not well-defined and need more research.
research Spontaneous cutaneous adverse drug reaction reports—An analysis of a 10‐year dataset in Singapore
In Singapore, most skin reactions to drugs were in females and Chinese, often caused by painkillers, antibiotics, and some other drugs, with serious cases linked to genetics.
research Cosmetic filler-induced hair loss: case series and literature review
Early treatment can help reverse hair loss caused by cosmetic fillers.
research The US FDA has approved the marketing of generic finasteride 5mg tablets by Actavis.
research Repurposed Drugs: Current Trends in Drug Discovery
Drug repurposing speeds up development, cuts costs, and uses known safe drugs, but faces challenges like regulations and patents.
research Injectable hydrogel made from antler mesenchyme matrix for regenerative wound healing via creating a fetal-like niche
The hydrogel promotes better wound healing by creating a fetal-like environment.
research Synthesis of 5α-Reductase Special inhibitor Finasteride
Finasteride is made through a series of chemical reactions starting from a specific intermediate compound.
research Evaluation of Polymorphism Influence in the Finasteride
Different forms of finasteride dissolve and remain stable differently, affecting capsule quality.
research Screening of dermatology drugs for aberrant use‐patterns: An application of epidemiologic estimates and measures of inequality in drug use
Dermatology drug use in Denmark mostly follows expected patterns, but further checks are needed for any misuse.
research 5α-Reductase inhibitors alter steroid metabolism and may contribute to insulin resistance, diabetes, metabolic syndrome and vascular disease: a medical hypothesis
Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
research Acquired 11β-hydroxylase Deficiency by Inhaled Etomidate and its Analogues: A Mimic of Congenital Adrenal Hyperplasia
Inhaled substances in e-cigarettes can cause hormone imbalances similar to congenital adrenal hyperplasia.
research Validated RP-TLC Method with Densitometry for Assay of Finasteride in Simple Pharmaceutical Dosage Form
A new, simple, and accurate method was created to measure finasteride in tablets.
research AN EFFICIENT SYNTHESIS OF DUTASTERIDE: UTILIZING BENZOYL GROUP AS NOVEL LACTAMIC PROTECTING GROUP
Researchers created a new, efficient way to make Dutasteride, a hair loss and prostate drug, with high purity using a benzoyl group.
research Microneedle-Mediated Transdermal Drug Delivery for the Treatment of Multiple Skin Diseases
Microneedles improve drug delivery for skin diseases, enhancing treatment effectiveness and patient compliance.
research Optimized skin optical clearing for optical coherence tomography monitoring of encapsulated drug delivery through the hair follicles
A PEG-400/oleic acid mixture best improves drug delivery monitoring through hair follicles.
research SAT0631-HPR WHEN CAN I STOP MY STEROIDS? THE PATIENT PERSPECTIVE ON GLUCOCORTICOID USAGE IN ADULT INFLAMMATORY MYOPATHY
Patients need better information about the risks of long-term steroid use.
research A Single Intradermal Injection of Autologous Adipose-Tissue-Derived Stem Cells Rejuvenates Aged Skin and Sharpens Double Eyelids
Injecting a person's own fat stem cells into their skin can make it look younger and improve double eyelids for over a year.
research Methotrexate injection site reactions: Case report and literature review
Methotrexate injection site reactions are rare but can be managed by changing injection sites and using topical treatments.
research Fentanyl in hair. Chemical factors involved in accumulation and retention of fentanyl in hair after external exposure or in vivo deposition.
Fentanyl accumulates differently in hair from internal use compared to external exposure.
research High-performance liquid chromatographic method for the determination of finasteride in human plasma at therapeutic doses
Reliable method detects finasteride in human plasma at low doses.
research Alopecia Induced by Autologous Fat Injection into the Temporal Area: Case Report and Review of the Literature
Fat injections in the face can cause hair loss.
research Editorial: Biomedical advances in ultrasound-mediated drug/molecule delivery
Ultrasound can improve targeted drug delivery, making treatments more effective with fewer side effects.
research Mixing the Old with the New: Drug Repurposing for Immune Deficiency in the Era of Precision Medicine and Pediatric Genomics
Using old drugs for new uses can help treat rare immune deficiencies.