research Histologic and Cell Kinetic Studies of Hair Loss and Subsequent Recovery Process of Human Scalp Hair Follicles Grafted onto Severe Combined Immunodeficient Mice
Stem cells are key for hair follicle recovery.
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research STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone
The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.
research Active mitochondria in healthy spiny mouse fibroblasts resemble megamitochondria and remain resilient across lifespan
Spiny mice have resilient, large mitochondria that help them regenerate tissue.
research On Photo-Stability of Oxybenzone
Estrogen receptors may not affect mouse hair growth as previously thought, and oxybenzone in sunscreen is stable in sunlight.
research The role of somatostatin expression in hair follicle immune privilege
Somatostatin helps hair follicles suppress immune responses, which might aid in treating certain hair loss conditions.
research Molecular heterogeneity of quiescent melanocyte stem cells revealed by single‐cell RNA‐sequencing
Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.
research Hair Graying as an Evolutionary Checkpoint against Malignancy: a Stem Cell Perspective
Hair graying may help prevent cancer by protecting stem cells.
research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity
The human scalp hair bulb contains different types of melanocytes with varying abilities to produce melanin.
research Research Snippets
New hair regrowth model proposed, imiquimod found to kill skin cancer cells, T-cadherin loss linked to invasive skin cancer, no clear gene link to skin cancer after transplant, and study on children's hair loss shows male dominance and genetic ties.
research ABSENCE OF H2O2 BREAKDOWN IN HUMAN HAIR MEDULLA IMPLICATIONS IN FOLLICULAR MELANOGENESIS
Human hair medulla doesn't break down hydrogen peroxide, which may affect hair color formation.
research Exploring the Relationship Between Immune Cells and Non-Scarring Hair Loss: A Mendelian Randomization Study
Certain immune cells are linked to non-scarring hair loss, suggesting potential for immune-targeted treatments.
research Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration
Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
research Author response: Quantitative mapping of human hair greying and reversal in relation to life stress
Hair can naturally regain color after greying, and this change may be linked to stress levels.
research Human melanocyte development and melanoma dedifferentiation at single cell resolution
Human melanocytes have unique traits that affect melanoma development and prognosis.
research Deciphering the molecular morphology of the human hair cycle: Wnt signalling during the telogen–anagen transformation
Wnt signaling is important for the change from the resting phase to the growth phase in human hair cycles.
research Cell Population Dynamics in Wound-Induced Hair Follicle Neogenesis Model
Non-immune dermal cells dominate, epidermal cells increase after day 9, and certain immune cells persist beyond inflammation in wound-induced hair follicle regeneration.
research Nuclear Topology, Epigenetics, and Keratinocyte Differentiation
Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.
research Stem cell quiescence acts as a tumour suppressor in squamous tumours
Inactive hair follicle stem cells help prevent skin cancer.
research 319 Mechanisms of cell death regulation in hair regeneration
Blocking cell death in hair follicles can lead to impaired hair growth.
research Decision letter: Quantitative mapping of human hair greying and reversal in relation to life stress
Hair can naturally regain color, and stress might influence greying and its reversal.
research Some electron microscope observations on hardening in the human hair follicle
The hair follicle structure is more complex than thought, with new findings on protein formation.
research Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage
Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
research Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization
Reactive oxygen species (ROS) influence hair growth by causing DNA damage, cell death, and changes in immune cells.
research Genomic and anatomical comparisons of skin support independent adaptation to life in water by cetaceans and hippos
research An examination of a strand of 30,000 and 70,000 year old mammoth hair
Mammoth hair from different ages shows distinct surface textures and elemental compositions.
research Review of human hair optical properties in possible relation to melanoma development
Certain types of human hair might help ultraviolet rays reach and damage cells, possibly leading to melanoma.
research 1433 Epithelially derived, mitochondrial MPZL3 negatively regulates murine and human hair follicle cycling
A protein called MPZL3 in mitochondria slows down hair growth and could be a target for treating hair growth disorders.
research Locations of synthesis of hair structural proteins in human anagen follicles
Hair structural proteins are synthesized sequentially in specific cells, offering a new way to study hair proteins and defects.
research A Splice Site Mutation in the Gene of the Human Type I Hair Keratin hHa1 Results in the Expression of a Tailless Keratin Isoform
A genetic mutation in the hHa1 gene creates a smaller, but still functional, hair protein without causing hair problems.
research Variation in human hair ultrastructure among three biogeographic populations
Different populations have distinct hair structures related to their ancestry.