research Resident human dermal γδT-cells operate as stress-sentinels: Lessons from the hair follicle
Human dermal γδT-cells respond to stress in hair follicles, contributing to hair loss.
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research Alopecia areata: a review of diagnosis, pathogenesis and the therapeutic landscape
New treatments for alopecia areata show promise, but standardized guidelines are needed.
research Post-COVID-19 Syndrome Mechanisms, Prevention and Management
Long COVID causes lasting symptoms and needs vaccines for prevention and a team approach for treatment.
research SOCS3 treatment prevents the development of alopecia areata by inhibiting CD8+ T cell-mediated autoimmune destruction
SOCS3 treatment can prevent hair loss by stopping harmful immune responses.
research Pathological sequelae of long-haul COVID
Long-haul COVID can cause lasting symptoms affecting many body systems and may be linked to ongoing inflammation and immune system issues.
research Th1/Th2 PB balance and CD200 expression of patients with active severe alopecia areata
Patients with severe active alopecia areata have lower CD200 expression and an imbalance in their immune system.
research The potential of regulatory T cell-based therapies for alopecia areata
Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.
research Human Hair Follicle-Derived Mesenchymal Stromal Cells from the Lower Dermal Sheath as a Competitive Alternative for Immunomodulation
Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.
research Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways
Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.
research Advancements in Bioactive Compounds and Therapeutic Agents for Alopecia: Trends and Future Perspectives
New treatments for alopecia show promise in restoring hair growth by targeting immune and hormonal factors.
research ‘Omics’ Approaches for Studying the Microbiome in Alopecia Areata
Omics techniques are needed to understand the scalp microbiome's role in alopecia areata for new treatments.
research Stem cells tightly regulate dead cell clearance to maintain tissue fitness
Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
research EXPLORING THE ROLE OF UMBILICAL CORD AND CORD BLOOD IN REGENERATIVE MEDICINE
Umbilical cord and cord blood stem cells are promising for treating chronic diseases due to their versatility and ethical acceptability.
research Global behavior of solutions in a chemotaxis model for alopecia areata with signal-dependent sensitivity
Sparse hairless patches can develop and stabilize in alopecia areata under certain conditions.
research Melan-A Positive cells significantly expressed in immune-targeted follicles of Alopecia Areata
Melanocytes may trigger the immune response in alopecia areata, affecting hair regrowth.
research Nanocarrier Systems for Transdermal Drug Delivery
Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
research Construction of regulatory network for alopecia areata progression and identification of immune monitoring genes based on multiple machine-learning algorithms
Researchers found four genes that could help diagnose severe alopecia areata early.
research Inflammatory loops in the epithelial–immune microenvironment of the skin and skin appendages in chronic inflammatory diseases
Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.
research The hair follicle as a neuro-immuno-endocrine organ: Implications in hair disorders and regenerative therapies
Understanding hair follicle signaling can improve hair disorder treatments.
research Immune cell regulation of the hair cycle
Immune cells affect hair growth and could lead to new hair loss treatments.
research Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing
A humanized CXCL12 antibody may delay and treat alopecia areata by altering the immune response.
research Early prediction of alopecia areata using machine learning modeling of neuro stress immune signatures from multi datasets
A machine learning model can predict alopecia areata early using specific gene markers.
research Immune niches for hair follicle development and homeostasis
Immune cells are crucial for hair growth and preventing hair loss.
research Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata
Early intervention with JAK inhibitors may prevent alopecia areata progression.
research Therapeutic Application of Microsponges-based Drug Delivery Systems
Microsponges delivery system is a safe, versatile method for controlled drug release in various treatments.
research An immune regulatory CCT repeat containing oligodeoxynucleotide capable of causing hair loss in male mice
A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.
research Therapeutic Applications of Nanoemulsion Based Drug Delivery Systems: A Review of Patents in Last Two Decades
Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.
research Stem cells and aberrant signaling of molecular systems in skin aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
research Protective effects of finasteride on the pulmonary immune response in a combined model of trauma-hemorrhage and polymicrobial sepsis in mice
Finasteride helps reduce lung inflammation and damage after trauma and infection.
research Resting no more: re‐defining telogen, the maintenance stage of the hair growth cycle
The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.