research Another year in the grip of COVID‐19 with slow recovery
2021 saw a slow return to normalcy and increased scientific engagement despite COVID-19 challenges.
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research Follicular Targeting–A Promising Tool in Selective Dermatotherapy
Targeting hair follicles can improve skin treatments and reduce side effects.
research Editor’s picks January 2021
PrEP doesn't increase STI risk in high-risk men, anti-androgen drugs may lower ICU admission for male COVID-19 patients, a 3-point injection is better for crow's feet, and the 'Geriatric-8' tool could help assess frailty in older skin cancer patients.
research Immune niches for hair follicle development and homeostasis
Immune cells are crucial for hair growth and preventing hair loss.
research Immunolocalization of Epidermal Growth Factor Receptors in Normal Developing Human Skin
research Mechanical and Immunological Regulation in Wound Healing and Skin Reconstruction
Advances in mechanobiology and immunology could lead to scarless wound healing.
research Decision letter: IL18 signaling promotes homing of mature Tregs into the thymus
IL-18 signaling helps mature Tregs move into the thymus.
research Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies
Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
research 019 Herpes simplex virus infection in pemphigus patients: a prospective study
Herpes simplex virus infections should be considered in pemphigus patients to avoid unnecessary changes in treatment.
research Beyond vitiligo guidelines: combined stratified/personalized approaches for the vitiligo patient
Personalized treatment plans improve vitiligo care.
research Self Prion Protein Peptides are Immunogenic in Lewis Rats
Rats can develop an immune response to prion protein peptides, but it may cause severe skin issues in older rats.
research Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders
The immune processes causing VKH and vitiligo are similar in dogs and humans.
research Regulatory T cells in dominant immunologic tolerance
Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
research A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules
The assay effectively identifies compounds that affect immune cell activation.
research AB1511 SLE ONSET POST COVID-19 VACCINATION: COINCIDENTAL OR ASSOCIATION?
It's unclear if COVID-19 vaccination causes SLE; more research is needed.
research Intensive immunosuppression in patients with disseminated sclerosis. I. Clinical response.
Intensive immunosuppression can reduce relapse rates in multiple sclerosis patients, despite some side effects.
research Identification of differentially expressed miRNAs in alopecia areata that target immune-regulatory pathways
Certain microRNAs may help treat alopecia areata by targeting immune pathways.
research 1 Academic Pathways to a Practice in Facial Surgery
There are several educational routes to become a facial surgeon, each with different specializations and fellowships.
research Signaling pathways involved in hair follicle cycling and morphogenesis
Hair growth and development are controlled by complex signaling pathways.
research Nail Involvement inAutoimmune Bullous Disorders
The nail immune system is similar to hair but different from skin, with fewer immune markers.
research Identification and characterization of four immune-related signatures in keloid
Four specific genes are linked to keloid formation and could be potential treatment targets.
research The impact of human immunodeficiency virus-related diseases on pigmented skin types
HIV can cause skin disorders, which are often the first sign of infection, especially in people with darker skin.
research Principles of Therapy of Skin Diseases
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
research Morphological characteristics and notes of the skin in preclinical toxicity assessment
Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
research PLAU and SerpinB2 role in apoptosis in leprosy
PLAU and SerpinB2 affect cell death differently in various forms of leprosy and could be targets for new treatments.
research LB793 A phase 1, open-Label, single ascending dose study in healthy subjects of the safety, tolerability and pharmacokinetics of ASLAN004, a novel IgG anti-IL-13 receptor alpha 1 Inhibitor
ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.
research Application and progress of induced pluripotent stem in chronic wound healing: a narrative review
Induced pluripotent stem cells could improve chronic wound healing but face safety and effectiveness challenges.
research Recombinant human hepatitis B vaccine initiating alopecia areata: testing the hypothesis using the C3H/HeJ mouse model
The hepatitis B vaccine did not cause hair loss in the tested mice.
research Role of Transepidermal and Transfollicular Routes in Percutaneous Absorption of Steroids: In vitro Studies on Human Skin
Hair follicles and glands significantly increase steroid absorption in skin.
research JAK 1-3 inhibitors and TYK-2 inhibitors in dermatology: Practical pearls for the primary care physician
Primary care doctors need to monitor JAK and TYK-2 inhibitors carefully for skin conditions.