research Testosterone implants in women: Pharmacological dosing for a physiologic effect
Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
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research The Contribution of Endogenous and Exogenous Factors to Female Alopecia
Both genetic and lifestyle factors significantly affect female hair loss.
research Optimization of LC method for the determination of testosterone and epitestosterone in urine samples in view of biomedical studies and anti-doping research studies
Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.
research Exfoliative cutaneous lupus erythematosus in German shorthaired pointer dogs: disease development, progression and evaluation of three immunomodulatory drugs (ciclosporin, hydroxychloroquine, and adalimumab) in a controlled environment
Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.
research Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage
Honokiol helps protect skin from damage and aging caused by cigarette smoke.
research Angiogenin is expressed in human dermal papilla cells and stimulates hair growth
Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.
research Decreased lipin 1β expression in visceral adipose tissue is associated with insulin resistance in polycystic ovary syndrome
Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.
research Gender Differences in Skin Aging and the Changing Profile of the Sex Hormones with Age
The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.
research Insulin sensitivity, androgens and isotretinoin therapy in women with severe acne
Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.
research Defining hyperandrogenaemia according to the free androgen index in Chinese women: a cross-sectional study
FAI values above 6.4 may suggest high androgen levels and increased metabolic risks in Chinese women of reproductive age.
research Hair loss and hyperprolactinemia in women
Moderately high prolactin levels do not cause hair loss in women.
research Assessment, diagnosis and treatment of a patient with hirsutism
A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.
research Topical application of synthetic melanin promotes tissue repair
Synthetic melanin applied to skin speeds up wound healing.
research An investigation of crosstalk between Wnt/β-catenin and transforming growth factor-β signaling in androgenetic alopecia
Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.
research Low Starch/Low Dairy Diet Results in Successful Treatment of Obesity and Co- Morbidities Linked to Polycystic Ovary Syndrome (PCOS)
Eating less starch and dairy helped overweight women with PCOS lose weight and improve symptoms.
research Pharmacokinetics of a transdermal testosterone cream in healthy postmenopausal women
A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
research Expression of 11β-hydroxysteroid dehydrogenase type 1 in visceral and subcutaneous adipose tissues of patients with polycystic ovary syndrome is associated with adiposity
Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.
research Mechanism of Salutary Effects of Finasteride on Post-traumatic Immune/Inflammatory Response
Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.
research Relations between sex hormone level and characters of hair and skin in healthy young men
Higher androgen levels do not cause baldness in men.
research Minoxidil overdose with ecg changes: Case report and review
Minoxidil overdose caused heart changes, treated with stomach wash, charcoal, and IV fluids.
research Polycystic Ovary Syndrome in Adolescents
The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.
research High circulating oestrone and low testosterone correlate with adverse clinical outcomes in men with advanced liver disease
Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.
research Spironolactone in the Treatment of Hirsutism
Spironolactone can reduce hair growth and testosterone in hirsutism, but is less effective than combined treatments.
research Do Different Diagnostic Criteria Impact Polycystic Ovary Syndrome Diagnosis for Adolescents?
Different diagnostic criteria greatly affect PCOS diagnosis rates in teenagers.
research Wnt5a Suppresses β-catenin Signaling during Hair Follicle Regeneration
Wnt5a slows down hair growth by blocking a specific pathway during hair regeneration.
research Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities
Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.
research Association of premature androgenetic alopecia and metabolic syndrome in a young Indian population
Early hair loss links to metabolic issues in young Indian men.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today’s Pre-Clinical Data into Tomorrow’s Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Is prostate-specific antigen a potential new marker of androgen excess in polycystic ovary syndrome?
Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.
research Antiandrogen Drugs Lower Serum Prostate-Specific Antigen (PSA) Levels in Hirsute Subjects: Evidence That Serum PSA Is a Marker of Androgen Action in Women1
Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.