77 citations
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July 2020 in “Journal of the European Academy of Dermatology and Venereology” Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
77 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
76 citations
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February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
75 citations
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August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
75 citations
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January 1995 in “American journal of primatology” Vervet monkeys show physical changes like hair loss and scrotal color changes due to stress or nutrition issues.
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January 2013 in “Expert Opinion on Biological Therapy” The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.
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January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
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January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
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February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
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October 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
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August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
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February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
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January 2013 in “Frontiers in Immunology” The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
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September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
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August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
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May 2016 in “Experimental dermatology” FFA's causes may include environmental triggers and genetic factors.
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January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
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May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
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March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
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March 2017 in “Nature communications” Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.
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August 2014 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.
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January 1998 in “Drugs” Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.
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September 2010 in “Genomics” The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
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September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
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January 2014 in “Anais Brasileiros De Dermatologia” Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
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July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
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December 2005 in “Biomedical Papers” Hair analysis can detect drug use but requires careful interpretation due to its complexity.
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March 2013 in “Human Reproduction Update” Products should be called 'sperm-safe' only after thorough, well-designed tests.
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June 2018 in “Nutrients” Celiac disease can cause skin problems that may get better with a gluten-free diet.
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September 2017 in “Journal of controlled release” Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.