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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Apple extract called procyanidin B-2 was found to greatly increase hair growth.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Finasteride reduces prostate bleeding by affecting blood vessel growth.

LED light can help hair growth by activating specific cell pathways.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

Blocking certain fat production can reverse skin inflammation and hair loss.

Minoxidil helps prevent stress-caused hair loss in mice.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Tannic acid helps wounds heal faster in rats by activating certain cell signals and reducing inflammation.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.

CD10 and CD34 levels change during hair development and different hair growth stages, which could be important for hair regeneration treatments.

Loss of Pten in certain hair follicle stem cells increases skin cancer risk.

The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.

VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

The pituitary gland functions normally even after losing most SOX2+ stem cells.

Certain drugs can cause early hair growth in mice by affecting the nerves.

Modified stem cells from umbilical cord blood can make hair grow faster.