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Therapeutic Potential of Nerve Growth Factor-Modified Hair Follicle Stem Cells Transplantation in a Rat Model of Alzheimer's Disease

research Therapeutic Potential of Nerve Growth Factor-Modified Hair Follicle Stem Cells Transplantation in a Rat Model of Alzheimer’s Disease

February 2026 in “Journal of Integrative Neuroscience”

NGF-modified hair follicle stem cells may help treat Alzheimer's by improving brain function and reducing harmful proteins.

research Stingless bee propolis promotes hair follicle regeneration and melanocyte function in chemotherapy-induced alopecia mouse model

November 2025 in “EXPERIMENTAL ANIMALS”

Stingless bee propolis may help regenerate hair follicles and improve pigment function in chemotherapy-induced hair loss.

research Bioinformatics analysis and verification of m6A related genes based on the construction of keloid diagnostic model

January 2023 in “Research Square (Research Square)”

IGF2BP3 gene is up-regulated in keloid patients, suggesting potential targets for treatment.

Transplanted Hair Follicle Mesenchymal Stem Cells Alleviated Small Intestinal Ischemia–Reperfusion Injury via Intrinsic and Paracrine Mechanisms in a Rat Model

research Transplanted hair follicle mesenchymal stem cells alleviated small intestinal ischaemia–reperfusion injury via intrinsic and paracrine mechanisms in a rat model

June 2022 in “Research Square (Research Square)”

Hair follicle stem cells can help heal intestinal injuries in rats.

research 1455 Cutaneous wounds healed at the cost of overall fitness in the aged Balb/C mouse model

April 2018 in “Journal of Investigative Dermatology”

Older mice healed wounds better but lost more weight and might have weaker immune systems afterward.

Follicle Dermal Papilla Cells Undergo Chromatin Remodeling Processes In Vivo And In Vitro

research 252 Follicle dermal papilla cells undergo chromatin remodelling processes in vivo and in vitro

September 2017 in “Journal of Investigative Dermatology”

Hair follicle cells change their DNA packaging during growth cycles and when grown in the lab.

The Effect of Glycyrrhizic Acid and Aqueous Licorice Extract on Hair Growth Retardation: In Vitro Mechanistic and Efficacy Studies in Human

research The effect of glycyrrhizic acid and aqueous licorice extract on hair growth retardation : in vitro mechanistic and efficacy studies in human

January 2016

Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.

Intraovarian Platelet-Rich Plasma Administration Could Improve Blastocyst Euploidy Rates in Women Undergoing In Vitro Fertilization

research Intraovarian platelet-rich plasma administration could improve blastocyst euploidy rates in women undergoing in vitro fertilization

15 citations , August 2022 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine”

Platelet-rich plasma may improve embryo genetics in IVF.

Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro

research Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro

82 citations , January 2002 in “Journal of drug targeting”

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

Tea Tree Oil Concentration in Follicular Casts After Topical Delivery: Determination by High-Performance Thin Layer Chromatography Using a Perfused Bovine Udder Model

research Tea Tree Oil Concentration in Follicular Casts After Topical Delivery: Determination by High-Performance Thin Layer Chromatography Using a Perfused Bovine Udder Model

32 citations , November 2004 in “Journal of pharmaceutical sciences”

Different tea tree oil mixtures absorb into hair follicles at varying levels, with microemulsion being the most effective.

Developing New Dual-Action Antiviral/Anti-Inflammatory Small Molecules for COVID-19 Treatment Using In Silico and In Vitro Approaches

research DEVELOPING NEW DUAL-ACTION ANTIVIRAL/ANTI-INFLAMMATORY SMALL MOLECULES FOR COVID-19 TREATMENT USING IN SILICO AND IN-VITRO APPROACHES

November 2024

Hit15 shows promise as a COVID-19 treatment by reducing virus infection and inflammation.

research Investigation of the Cognitive Activity Between the Leaf Extracts of Eclipta alba and Ziziphus jujuba in Diabetic Animal Models

March 2024 in “Curēus”

Ziziphus jujuba and Eclipta alba leaf extracts improve blood sugar levels and cognitive function in diabetic rats.

research Investigation of the role of biotin in the regulation of wool growth in sheep hair follicle cultured in vitro

January 2007

Biotin boosts wool growth and follicle health in sheep.

Exosomes Facilitate mRNA and siRNA Delivery Using Cationic Liposomes 2X3-DOPE to Rat Heart Mesenchymal Cells In Vitro

research Exosomes facilitate mRNA and siRNA delivery using cationic liposomes 2X3-DOPE to rat heart mesenchymal cells in vitro

June 2025 in “Medical academic journal”

Modified liposomes with exosomes effectively deliver RNA to stem cells.

Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo

research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo

68 citations , December 2011 in “Journal of Investigative Dermatology”

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

research Promotive Effect of Minoxidil Combined with All-trans Retinoic Acid (tretinoin) on Human Hair Growth in Vitro

41 citations , January 2007 in “Journal of Korean Medical Science”

Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.

Thyrotropin-Releasing Hormone and Estrogen Differentially Regulate Prolactin and Prolactin Receptor Expression in Female Human Skin and Hair Follicles In Vitro

research Thyrotropin-releasing hormone and oestrogen differentially regulate prolactin and prolactin receptor expression in female human skin and hair follicles in vitro

37 citations , March 2010 in “British Journal of Dermatology”

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

research Foot shock stress prolongs the telogen stage of the spontaneous hair cycle in a non‐depilated mouse model
31 citations , April 2007 in “Experimental Dermatology”

Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.

research The 5α-reductase inhibitor Dutasteride but not Finasteride protects dopamine neurons in the MPTP mouse model of Parkinson’s disease
27 citations , May 2015 in “Neuropharmacology”

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

research Nuclear Factor I-C promotes proliferation and differentiation of apical papilla-derived human stem cells in vitro
24 citations , February 2015 in “Experimental Cell Research”

NFIC helps human dental stem cells grow and become tooth-like cells.

research Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture
23 citations , January 2020 in “Frontiers in Pharmacology”

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

research Ginsenoside F2 Reduces Hair Loss by Controlling Apoptosis through the Sterol Regulatory Element-Binding Protein Cleavage Activating Protein and Transforming Growth Factor-β Pathways in a Dihydrotestosterone-Induced Mouse Model
22 citations , January 2014 in “Biological & Pharmaceutical Bulletin”

Ginsenoside F2 may help prevent hair loss and promote hair growth better than finasteride.

research Miniaturized hairs maintain contact with the arrector pili muscle in alopecia areata but not in androgenetic alopecia: A model for reversible miniaturization and potential for hair regrowth
22 citations , July 2012 in “International Journal of Trichology”

Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.

research Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems
17 citations , December 2019 in “Stem Cell Research & Therapy”

Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.

research Development of finasteride/PHBV@polyvinyl alcohol/chitosan reservoir-type microspheres as a potential embolic agent: from in vitro</i> evaluation to animal study
14 citations , January 2020 in “Biomaterials Science”

Created microspheres show potential for safe and effective use in prostate artery embolization.

research Immunocytochemical Localization of Androgen Receptors in the Scalp of the Stumptail Macaque Monkey, a Model of Androgenetic Alopecia
13 citations , April 1994 in “Journal of Investigative Dermatology”

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

research The 5α-reductase inhibitor finasteride increases suicide-related aggressive behaviors and blocks clozapine-induced beneficial effects in an animal model of schizophrenia
12 citations , April 2018 in “Physiology & Behavior”

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

research In vitro Assembly Properties of Human Type I and II Hair Keratins
12 citations , January 2014 in “Cell structure and function”

Different combinations of human hair keratins affect how hair fibers form.

research Effects of 1?,25-dihydroxy-vitamin D3 and calcipotriol on organotypic cultures of outer root sheath cells: a potential model to evaluate antipsoriatic drugs
10 citations , October 1993 in “Archives of dermatological research”

Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.

research Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model
9 citations , August 2024 in “Tissue Engineering and Regenerative Medicine”

Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.

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Research

research Therapeutic Potential of Nerve Growth Factor-Modified Hair Follicle Stem Cells Transplantation in a Rat Model of Alzheimer’s Disease

research Stingless bee propolis promotes hair follicle regeneration and melanocyte function in chemotherapy-induced alopecia mouse model

research Bioinformatics analysis and verification of m6A related genes based on the construction of keloid diagnostic model

research Transplanted hair follicle mesenchymal stem cells alleviated small intestinal ischaemia–reperfusion injury via intrinsic and paracrine mechanisms in a rat model

research 1455 Cutaneous wounds healed at the cost of overall fitness in the aged Balb/C mouse model

research 252 Follicle dermal papilla cells undergo chromatin remodelling processes in vivo and in vitro

research The effect of glycyrrhizic acid and aqueous licorice extract on hair growth retardation : in vitro mechanistic and efficacy studies in human

research Intraovarian platelet-rich plasma administration could improve blastocyst euploidy rates in women undergoing in vitro fertilization

research Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro

research Tea Tree Oil Concentration in Follicular Casts After Topical Delivery: Determination by High-Performance Thin Layer Chromatography Using a Perfused Bovine Udder Model

research DEVELOPING NEW DUAL-ACTION ANTIVIRAL/ANTI-INFLAMMATORY SMALL MOLECULES FOR COVID-19 TREATMENT USING IN SILICO AND IN-VITRO APPROACHES

research Investigation of the Cognitive Activity Between the Leaf Extracts of Eclipta alba and Ziziphus jujuba in Diabetic Animal Models

research Investigation of the role of biotin in the regulation of wool growth in sheep hair follicle cultured in vitro

research Exosomes facilitate mRNA and siRNA delivery using cationic liposomes 2X3-DOPE to rat heart mesenchymal cells <i>in vitro</i>

research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo

research Promotive Effect of Minoxidil Combined with All-trans Retinoic Acid (tretinoin) on Human Hair Growth in Vitro

research Thyrotropin-releasing hormone and oestrogen differentially regulate prolactin and prolactin receptor expression in female human skin and hair follicles in vitro</i>

research Foot shock stress prolongs the telogen stage of the spontaneous hair cycle in a non‐depilated mouse model

research The 5α-reductase inhibitor Dutasteride but not Finasteride protects dopamine neurons in the MPTP mouse model of Parkinson’s disease

research Nuclear Factor I-C promotes proliferation and differentiation of apical papilla-derived human stem cells in vitro

research Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture

research Ginsenoside F2 Reduces Hair Loss by Controlling Apoptosis through the Sterol Regulatory Element-Binding Protein Cleavage Activating Protein and Transforming Growth Factor-β Pathways in a Dihydrotestosterone-Induced Mouse Model

research Miniaturized hairs maintain contact with the arrector pili muscle in alopecia areata but not in androgenetic alopecia: A model for reversible miniaturization and potential for hair regrowth

research Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems

research Development of finasteride/PHBV@polyvinyl alcohol/chitosan reservoir-type microspheres as a potential embolic agent: from in vitro</i> evaluation to animal study

research Immunocytochemical Localization of Androgen Receptors in the Scalp of the Stumptail Macaque Monkey, a Model of Androgenetic Alopecia

research The 5α-reductase inhibitor finasteride increases suicide-related aggressive behaviors and blocks clozapine-induced beneficial effects in an animal model of schizophrenia

research <i>In vitro</i> Assembly Properties of Human Type I and II Hair Keratins

research Effects of 1?,25-dihydroxy-vitamin D3 and calcipotriol on organotypic cultures of outer root sheath cells: a potential model to evaluate antipsoriatic drugs

research Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model