December 2023 in “Aggregate” Scientists are using clumps of special stem cells to improve organ repair.
15 citations
,
February 2021 in “Scientific Reports” A specific group of stem cells can help regenerate hair continuously.
16 citations
,
March 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
8 citations
,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
29 citations
,
January 2016 in “Annals of dermatology/Annals of Dermatology” Arachidonic acid helps hair grow by increasing growth factors and improving follicle health.
26 citations
,
January 2019 in “Experimental Dermatology” Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
79 citations
,
January 2015 in “Journal of Materials Chemistry B” Smart biomaterials that guide tissue repair are key for future medical treatments.
17 citations
,
January 1997 in “Cell and Tissue Research” Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
15 citations
,
May 2023 in “npj Regenerative Medicine” Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
6 citations
,
December 2021 in “Scientific Reports” Inhibiting class I HDACs helps maintain hair growth ability in skin cells.
4 citations
,
February 2021 in “Nano select” MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
September 2022 in “Research Square (Research Square)” Macrophages help maintain mammary stem cells and balance through specific signaling.
April 2017 in “Journal of Investigative Dermatology” Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.
May 2015 in “Journal of Investigative Dermatology” Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.
April 2015 in “Plastic and Reconstructive Surgery” Activating TLR3 helps improve skin and hair follicle regeneration after wounds.
165 citations
,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
149 citations
,
July 2017 in “PLoS Biology” Hair follicle patterns form through a mix of self-organization and signaling interactions.
131 citations
,
July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
92 citations
,
August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
81 citations
,
January 2003 in “The FASEB Journal” Follistatin helps hair growth and cycling, while activin prevents it.
57 citations
,
March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
48 citations
,
February 2016 in “Scientific Reports” Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
46 citations
,
January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
40 citations
,
June 2013 in “Biomaterials” Scientists created 3D hair-like structures that could help study hair growth and test treatments.
27 citations
,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
24 citations
,
November 2016 in “Cell death and disease” Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
15 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
9 citations
,
December 2002 in “Novartis Foundation Symposium” LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.
7 citations
,
April 2013 in “Journal of Cellular Biochemistry” CD61 is important for mouse tooth cell growth and works through Lgr5.
7 citations
,
January 2013 in “BioMed research international” Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.