research DERMAL-EPIDERMAL INTERACTIONS
Hair loss is mainly caused by hormones, autoimmune issues, and chemotherapy, and needs more research for treatments.
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210-240 / 1000+ resultsresearch Recent advances in understanding the role of the skin microbiome in the treatment of atopic dermatitis
The skin microbiome plays a key role in treating atopic dermatitis.
research In vitro identification of a stem cell population from canine hair follicle bulge region
Researchers found stem cells in dog hair follicles using specific markers.
research A Mouse Model for Studying Stem Cell Effects on Regeneration of Hair Follicle Outer Root Sheaths
The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
research A new in vitro culture system to produce a fully differentiated epidermis from human hair follicle outer root sheath cells
Researchers developed a method to grow skin-like tissue from hair cells.
research Intracrine androgen biosynthesis, metabolism and action revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
research Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
research Hair follicle-derived mesenchymal stem cells decrease alopecia areata mouse hair loss and reduce inflammation around the hair follicle
Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
research Early prediction of alopecia areata using machine learning modeling of neuro stress immune signatures from multi datasets
A machine learning model can predict alopecia areata early using specific gene markers.
research 0873 Modeling junctional epidermolysis bullosa using tissue-engineered skin substitutes
Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.
research Skin toxicity determined in vitro by three-dimensional, native-state histoculture.
This model can replace animal testing for quick, cost-effective skin toxicity tests.
research Decision letter: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes
Moles may stop growing due to cell cooperation, not just because of individual cell aging.
research 918 Tissue engineered human hair follicles from genetically, environmentally and extrinsically reprogrammed dermal papilla cells
Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
research A new hair follicle-derived human epidermal model for the evaluation of sunscreen genoprotection
The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
research Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro
A 3D skin model helps study wound healing better than traditional methods.
research Biofabrication Technologies in Hair Neoformation
New biofabrication technologies could lead to treatments for hair loss.
research The study of improvement of hair follicle stem cells of rats in vitro culture identification and differentiation
Rat hair follicle stem cells can be effectively isolated and used for tissue engineering.
research 1315 An Integrated model of alopecia areata biomarkers highlights both Th1/Th2 upregulation, with stronger correlations between Th2 activation and disease severity
Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.
research Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing
Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
research Towards developing an organotypic model for the preclinical study and manipulation of human hair matrix-dermal papilla interactions
The study created a new model to better understand human hair growth and health.
research A simple method using ex vivo culture of hair follicle tissue to investigate intrinsic circadian characteristics in humans
Researchers developed a way to study human body clocks using hair tissue, which works similarly in both healthy and dementia patients.
research Generation of Hair Follicle Germs In Vitro Using Human Postnatal Skin Cells
Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.
research Multi-faceted enhancement of full-thickness skin wound healing by treatment with autologous micro skin tissue columns
Using micro skin tissue columns improves skin wound healing and reduces scarring.
research Hair growth promoting effects of adipose tissue-derived stem cells
Fat tissue stem cells may help increase hair growth.
research Prevascularization of dermal substitutes with adipose tissue-derived microvascular fragments enhances early skin grafting
Using adipose tissue-derived fragments improves early skin graft success.
research Phosphatidic Acid Has a Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells
Phosphatidic acid may help hair grow by affecting cell growth pathways.
research 5α-Reductase Inhibitors, Chemical and Clinical Models
Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
research Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model
50-mg ritlecitinib capsules are bioequivalent to 100-mg capsules.
research Tooth tissue and organ regeneration using stem cells
Stem cell-based therapies can regenerate and replace teeth effectively.
research Internal peacekeepers and external mediators: A new model of peripheral immune tolerance involving regulatory T cells and mesenchymal stem cells
Regulatory T cells and mesenchymal stem cells work together to prevent immune system overreactions and tissue damage.