63 citations
,
May 2009 in “Dermato-endocrinology” Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.
31 citations
,
September 1999 in “Molecular Carcinogenesis” Increased ornithine decarboxylase makes normally tumor-resistant mice more sensitive to tumors.
23 citations
,
September 2013 in “Molecular Carcinogenesis” Increased Stat3 activity reduces hair follicle stem cells and boosts other stem/progenitor cells.
22 citations
,
April 2006 in “Journal of Dermatological Science” Vitamin C derivative increases versican in cells, potentially aiding hair growth.
21 citations
,
July 2015 in “International Journal of Nanomedicine” Increased liposome fluidity boosts skin penetration of sodium fluorescein.
20 citations
,
August 1997 in “PubMed” Increased K+ permeability alone may not promote hair growth.
18 citations
,
December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.
17 citations
,
July 2013 in “Amino Acids” Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
14 citations
,
April 2008 in “PROTEOMICS” Increased 14-3-3 proteins may block hair cycle regression, causing hair loss.
13 citations
,
December 1987 in “British Journal of Dermatology” Increased T cell activity may predict hair regrowth success with minoxidil in severe alopecia areata.
13 citations
,
March 2019 in “Pharmacology Research & Perspectives” In Singapore, most skin reactions to drugs were in females and Chinese, often caused by painkillers, antibiotics, and some other drugs, with serious cases linked to genetics.
12 citations
,
March 2016 in “BBA clinical” Increased Toll-like receptors in blood cells may contribute to alopecia areata and could be a target for new treatments.
10 citations
,
July 2008 in “Journal of Cutaneous Pathology” Increased mucin in the skin might indicate lupus in patients with hair loss, but more research is needed.
8 citations
,
June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
7 citations
,
May 2021 in “EBioMedicine” Increased methylation of the Filip1l gene may contribute to aggressive skin cancer.
7 citations
,
January 2015 in “Biological & Pharmaceutical Bulletin” Rice Bran Supercritical CO2 Extract significantly increased hair density and diameter in male alopecia patients without any side effects.
5 citations
,
March 2023 in “Archives of dermatological research” Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
2 citations
,
September 2021 in “Anais Brasileiros de Dermatologia” Increased sunscreen use may be linked to frontal fibrosing alopecia in Hispanic females.
April 2025 in “Dermatology Practical & Conceptual” Increased LC3 gene expression may be linked to premature graying of hair.
June 2024 in “Research Square (Research Square)” Increased cell death and reduced cell growth in hair follicles contribute to baldness.
December 2023 in “Journal of Thoracic Disease” Increased EGFR gene variations may predict chemotherapy outcomes in small cell lung cancer patients.
September 2023 in “Journal of the American Academy of Dermatology” Increased awareness and research are needed to prevent hair loss from cosmetic procedures.
September 2023 in “Journal of the American Academy of Dermatology” Increased Treg cells and IL-10 may help quick recovery in acute diffuse and total alopecia.
Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.
January 2019 in “AYBU AVESIS” Increased oxidative stress and decreased antioxidants contribute to hair loss in androgenetic alopecia.
January 2012 in “Chinese Journal of Aesthetic Medicine” Increased androgen receptor expression in certain hair follicle areas may cause male pattern baldness.
June 2004 in “Journal of Investigative Dermatology” Increased pigmentation may protect skin from UVB, new targets for skin disease treatments were identified, sunscreen ingredients don't affect hormones, TNF-α inhibitors may help diabetic wounds, and certain treatments could prevent chemotherapy-induced hair loss.
January 2004 in “Giornale di Metafisica: revista bimestrale di filosofia” Increased Wnt signaling causes hair graying by depleting melanocyte stem cells in aged mice.
September 1999 in “Molecular Carcinogenesis” Increased ODC expression makes normally tumor-resistant mice more prone to tumor development.
July 1998 in “Chromatographia” Women with effluvium have higher levels of certain urinary steroids, possibly due to stress and increased adrenal activity.