research Non-clinical safety evaluation and risk assessment to human of aleglitazar, a dual PPAR α/γ agonist, and its major human metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
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research C‐tactile afferents: The mystery of human emotional touch has been hidden hair‐deep
C-tactile afferents are linked to emotional touch and social bonding through hair movement.
research 52993 Regulatory γδ T cells protect human scalp hair follicles from alopecia areata in vivo
Regulatory γδ T cells help protect hair follicles from alopecia areata and promote hair regrowth.
research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration
ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
research Generation of folliculogenic human epithelial stem cells from induced pluripotent stem cells
Scientists created stem cells that can grow hair and skin.
research XMU-MP-1 induces growth arrest in a model human mini-organ and antagonises cell cycle-dependent paclitaxel cytotoxicity
XMU-MP-1 stops cell growth in a human mini-organ and reduces the effectiveness of the chemotherapy drug paclitaxel.
research 709 Synthetic developmental tissue engineering of human hair follicles
Scientists have found a way to grow hair follicles from human cells in a lab, which could help treat hair loss and skin damage.
research Immunohistochemical localization of types 1 and 2 5α-reductase in human scalp
The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.
research Hair cortisol in drug-naïve first-episode individuals with psychosis
First-episode psychosis patients have higher hair cortisol levels, indicating early stress response issues.
research Characterization and isolation of stem cell-enriched human hair follicle bulge cells
Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
research Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation
Fat under the skin releases HGF which helps hair grow and gain color.
research Review of the effects of 17α-estradiol in humans: a less feminizing estrogen with neuroprotective potential
17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
research Model systems for the study of dermatophyte and non-dermatophyte invasion of human keratin.
Terbinafine effectively stops fungal invasion of human keratin.
research Robust coupling between the C‐tactile afferent and the hair follicle in humans
C-tactile nerves are sensitive to hair movement.
research Lactobacillus paracasei HY7015 and Lycopus lucidus Turcz. Extract Promotes Human Dermal Papilla Cell Cytoprotective Effect and Hair Regrowth Rate in C57BL/6 Mice
The substances improved hair regrowth and protected hair cells in humans and mice.
research Enhancing Hairfall Prediction: A Comparative Analysis of Individual Algorithms and An Ensemble Method
Combining multiple algorithms predicts hair fall more accurately than using single algorithms.
research Application of extracellular vesicles from mesenchymal stem cells promotes hair growth by regulating human dermal cells and follicles
Using extracellular vesicles from stem cells can help hair grow by affecting scalp cells and hair follicles.
research Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis
Certain mutations in a hair growth-related gene cause a type of genetic hair loss.
research Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture
A reliable system was developed to distinguish hair growth stages, aiding in identifying hair growth promoters or inhibitors.
research Prolactin—a novel neuroendocrine regulator of human keratin expressionin situ
Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
research Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle
Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.
research Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding?
TGase 3 helps build hair structure by forming strong bonds between proteins.
research Molecular Analysis of the ABCA4 Gene Mutations in Patients with Stargardt Disease Using Human Hair Follicles
Hair follicles can be used to study gene mutations in Stargardt disease.
research Identification of Bulge Stem Cells in Mouse and Human Hair Follicles
Scientists found markers called CD34 and CD200 that help identify stem cells in mouse and human hair follicles.
research Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata
ILC1-like cells can cause alopecia areata by attacking hair follicles.
research Somatic mutations distinguish melanocyte subpopulations in human skin
Hair follicles protect melanocytes from sun damage, helping them replenish skin.
research Local synthesis and effect of sex steroids in human skin and the hair follicle and hormonal effects on the wound healing response
Local estrogen synthesis in skin may improve wound healing.
research Maternal nutrition at conception modulates DNA methylation of human metastable epialleles
A mother's diet at conception can cause lasting genetic changes in her child.
research New topical antiandrogenic formulations can stimulate hair growth in human bald scalp grafted onto mice
Topical treatments can regrow hair on bald scalps.
research Ectodysplasin-A2 induces dickkopf 1 expression in human balding dermal papilla cells overexpressing the ectodysplasin A2 receptor
A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.