iEdgePathDDA effectively finds new drug-disease links, outperforming other methods.
January 2005 in “Fuzhou daxue xuebao. Ziran kexue ban” The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.
January 1985 in “Clinical research” Topical alpha-terthienyl with UVA may safely treat psoriasis without cancer risk.
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September 2017 in “Oncotarget” A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
102 citations
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October 2010 in “Molecular Pharmaceutics” Copper-doxorubicin nanoparticles effectively treat tumors with less toxicity.
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August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
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February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
68 citations
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September 2018 in “Trends in Cell Biology” Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
65 citations
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April 2021 in “Natural Products and Bioprospecting” Dendrobium plants have compounds useful for treating skin issues and developing new drugs and cosmetics.
60 citations
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November 2009 in “General and Comparative Endocrinology” Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
48 citations
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May 2021 in “Molecules” Plant extracts from dry flowers can be used as safe, effective dyes in cosmetics, offering skin protection and anti-aging benefits.
48 citations
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August 2018 in “Nature Communications” JunB is crucial for maintaining healthy skin and hair follicles.
46 citations
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June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
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December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
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June 2013 in “Molecular Pharmaceutics” The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.
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May 2013 in “Andrologia” Some herbs show promise as antiandrogenic agents.
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March 2006 in “Seminars in cutaneous medicine and surgery” The document explains how to identify different hair problems using a microscope.
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December 2017 in “Journal of Drug Delivery Science and Technology” Minoxidil and caffeine in transfersomes improve hair growth treatment.
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September 2002 in “The Journal of Comparative Neurology” Presynaptic inhibition of certain nerve fibers in cats is mainly controlled by GABA and glycine.
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May 2018 in “Journal of Cosmetic Dermatology” Costunolide helps human hair cells grow and can stimulate hair growth in mice.
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May 2005 in “Journal of the American Veterinary Medical Association” The exact cause of growth hormone-responsive alopecia in dogs is unclear.
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August 1960 in “British journal of dermatology/British journal of dermatology, Supplement” Endoxan often causes hair loss, which usually starts in the third week of treatment.
20 citations
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March 2005 in “Current Medicinal Chemistry” New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
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February 2023 in “Plants” Purple glutinous rice extracts can help whiten skin and reduce aging signs.
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October 2015 in “The Journal of Physiology” Combining progesterone with caffeine worsens breathing issues in newborns.
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June 2019 in “Journal of Neuroendocrinology” Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.
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January 2010 in “Experimental Dermatology” Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.
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March 2017 in “Genes and immunity” Certain microRNAs may help treat alopecia areata by targeting immune pathways.
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January 2008 in “Gene therapy” Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.
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March 2004 in “Der Urologe” There is no strong evidence that chemopreventive agents effectively prevent prostate cancer.