research In This Issue
Advancements in hair biology include new treatments and tools for hair growth and alopecia.
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research Transepidermal UV radiation of scalp skin ex vivo induces hair follicle damage that is alleviated by the topical treatment with caffeine
Caffeine applied to the scalp can protect hair follicles from UV damage.
research In vivohair growth-stimulating effect of medicinal plant extract on BALB/c nude mice
Chrysanthemum zawadskii extract may be a better treatment for hair loss than Minoxidil.
research Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth
Low ERCC3 gene activity is linked to non-pigmented hair growth.
research Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles in vitro
Gambogic Amide helps maintain hair color and promotes hair growth.
research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
research Construction of regulatory network for alopecia areata progression and identification of immune monitoring genes based on multiple machine-learning algorithms
Researchers found four genes that could help diagnose severe alopecia areata early.
research Signaling pathways in hair aging
Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.
research Alopecia areata in a rhesus monkey (Macaca mulatta)
The monkey's hair loss was due to an autoimmune disease, not genetics.
research Molecular Basis for Hair Loss in Mice Carrying a Novel Nonsense Mutation (Hrrh-R) in the Hairless Gene (Hr)
A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.
research Androgens and hair growth
Androgens can both increase and decrease hair growth in different parts of the body.
research Possible mechanisms of miniaturization during androgenetic alopecia or pattern hair loss
Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
research Ectopic Expression of the nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia
The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
research The role of lymphocytes in the development and treatment of alopecia areata
Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
research Hair removal using an Nd: YAG laser system.
Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.
research Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development
Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
research Promotion Effect of Apo-9′-fucoxanthinone from <i>Sargassum muticum</i> on Hair Growth <i>via</i> the Activation of Wnt/β-Catenin and VEGF-R2
Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.
research CD133-positive dermal papilla-derived Wnt ligands regulate postnatal hair growth
Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
research The Effect of Parathyroid Hormones on Hair Follicle Physiology: Implications for Treatment of Chemotherapy-Induced Alopecia
Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.
research KF19418, a new compound for hair growth promotion in vitro and in vivo mouse models
KF19418 promotes hair growth similarly to minoxidil but is not better in live mice.
research Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury
mTORC1 signaling needed for quick hair follicle recovery after radiation damage.
research Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators
The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
research Regeneration of hair and other skin appendages: A microenvironment‐centric view
The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
research Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Proposed mechanisms of low-level light therapy in the treatment of androgenetic alopecia
LLLT helps treat hair loss by increasing blood flow, reducing inflammation, and stimulating growth factors.
research Promotion of hair growth by newly synthesized ceramide mimetic compound
A new compound, BOI, can help hair grow by changing hair cycle phases and increasing certain cell contents.
research Androgens and hair: a biological paradox with clinical consequences
Androgens can both increase body hair and cause scalp hair loss.
research Morphological characteristics and notes of the skin in preclinical toxicity assessment
Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
research The pathogenesis of alopecia areata
Alopecia areata is an autoimmune disease affecting hair follicles and may harm heart health.
research Hair growth promoting effect and action mechanism of Chrysanthemum zawadskii extract
Chrysanthemum zawadskii extract may help treat hair loss by promoting hair growth and affecting growth factors.