April 2019 in “Journal of Investigative Dermatology” The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.
87 citations
,
July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
2 citations
,
March 2018 in “Biotechnology Letters” Scientists created a new cell line from Cashmere goat hair and found that cytokeratin 13 is a unique marker for certain skin cells.
34 citations
,
April 2018 in “EMBO journal” The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
32 citations
,
February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
169 citations
,
May 2006 in “Genes & Development” Keratin 17 is crucial for normal hair growth by regulating hair cycle transitions with TNFα.
26 citations
,
May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
9 citations
,
February 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.
2 citations
,
January 2011 in “Dental Medicine Research” Keratin 75 might be important in oral cancer progression.
156 citations
,
January 1989 in “Genes & Development” Keratin expression reflects cell organization and differentiation, not causes it.
98 citations
,
June 2001 in “Journal of biological chemistry/The Journal of biological chemistry” A cluster of sulfur-rich hair protein genes was found on chromosome 17.
7 citations
,
July 2008 in “Experimental Dermatology” The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.
4 citations
,
June 2020 in “British Journal of Pharmacology” Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.
2 citations
,
January 2017 in “Folia biologica” The KRTAP7-1 gene is very similar across different cattle and yak breeds and likely plays a role in hair strength and shape.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.
28 citations
,
March 2010 in “Histochemistry and cell biology” Skin cells can help create early hair-like structures in lab cultures.
6 citations
,
September 2009 in “European journal of histochemistry” CD90 is present on specific cells in dog hair follicles.
9 citations
,
July 2013 in “Experimental Dermatology” Aging reduces the ability of human hair follicle cells to form new cell colonies.
122 citations
,
June 2002 in “Genes & Development” Keratin 17 is crucial for early hair strength and cell survival.
2 citations
,
August 2020 in “Clinical, Cosmetic and Investigational Dermatology” The hair-growth formula with L-cystine helps protect and grow hair cells.
4 citations
,
September 2012 in “Journal of dermatological science” The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.
December 2018 in “IntechOpen eBooks” Neurohormones help control skin health and could treat skin disorders.
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
January 2012 in “Durham e-Theses (Durham University)” Keratin 15 affects cell behavior and characteristics in skin cells.
April 2017 in “Journal of Investigative Dermatology” Scientists can control how skin stem cells divide by using different treatments.
54 citations
,
November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
28 citations
,
April 1996 in “Cell biology international” Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
9 citations
,
January 2021 in “RSC Advances” Non-thermal plasma helps hair grow by improving the area around hair follicles.
53 citations
,
September 1999 in “The journal of cell biology/The Journal of cell biology” K16 can partially replace K14 but causes hair loss and skin issues.
14 citations
,
September 1991 in “Journal of Investigative Dermatology” Minoxidil slows down keratinocyte growth without being toxic.