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Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review

research Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review

343 citations , December 2008 in “Endocrine Reviews”

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

research Mechanical stretch induces hair regeneration through the alternative activation of macrophages

163 citations , April 2019 in “Nature Communications”

Mechanical stretching of the skin can promote hair growth by activating certain immune cells.

research GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE

90 citations , October 1996 in “Dermatologic Clinics”

Growth factors are crucial for hair development and could help treat hair diseases.

Mechanisms of Disease: Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 as a Novel Treatment for Metabolic Syndrome

research Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome

69 citations , December 2005 in “Nature Clinical Practice Endocrinology & Metabolism”

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

research Ghrelin levels are suppressed and show a blunted response to oral glucose in women with polycystic ovary syndrome.

44 citations , March 2008 in “European journal of endocrinology”

Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.

research Enhancement of Human Hair Growth UsingEcklonia cavaPolyphenols

26 citations , January 2016 in “Annals of Dermatology”

Ecklonia cava polyphenols help increase human hair growth and reduce hair loss.

research Polycystic ovary syndrome and risks for COVID-19 infection: A comprehensive review

24 citations , February 2022 in “Reviews in Endocrine and Metabolic Disorders”

Women with PCOS have a higher risk of severe COVID-19 due to related health issues.

research Protective Role of Nutritional Plants Containing Flavonoids in Hair Follicle Disruption: A Review

24 citations , January 2020 in “International Journal of Molecular Sciences”

Some plants with flavonoids may help treat hair loss and promote hair growth.

The Effect of Lactobacillus Plantarum Hydrolysates Promoting VEGF Production on Vascular and Hair Growth in C57BL/6 Mice

research The effect of Lactobacillus plantarum hydrolysates promoting VEGF production on vascular growth and hair growth of C57BL/6 mice

10 citations , April 2019 in “Journal of Analytical Science and Technology”

Lactobacillus plantarum hydrolysates may help increase hair growth by boosting VEGF production.

Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells

research Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells

9 citations , April 2019 in “International Journal of Molecular Sciences”

Kojyl cinnamate ester derivatives can promote hair growth by increasing adiponectin production in fat tissues.

The 'Bald' Phenotype (Androgenetic Alopecia) Is Caused by the High Glycemic, High Cholesterol, and Low Mineral 'Western Diet'

research The ‘bald’ phenotype (androgenetic alopecia) is caused by the high glycaemic, high cholesterol and low mineral ‘western diet’

7 citations , June 2021 in “Trends in Food Science and Technology”

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

research Cardiovascular profile of pharmacological agents used for the management of polycystic ovary syndrome

4 citations , January 2019 in “Therapeutic Advances in Endocrinology and Metabolism”

Medications for PCOS don't seem to raise heart disease risk.

research Psychiatric disorders in women with polycystic ovary syndrome

3 citations , September 2024 in “Journal of Pre-Clinical and Clinical Research”

Women with PCOS often experience mental health issues like depression and anxiety.

research Women’s Health Considerations for Lipid Management

3 citations , February 2016 in “Endocrinology and Metabolism Clinics of North America”

Manage women's cholesterol with diet, exercise, and careful treatment choices, especially during pregnancy, PCOS, and menopause.

research Role of Sodium–Glucose Cotransporter-2 Inhibitors in Managing Polycystic Ovary Syndrome: A Systematic Review

2 citations , January 2025 in “touchREVIEWS in Endocrinology”

SGLT2 inhibitors may help manage PCOS symptoms effectively.

research The Polycystic Ovary Syndrome - Challenges and Opportunities in Adolescent Medicine

1 citations , May 2009 in “Wiley-Blackwell eBooks”

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

research Polycystic ovary syndrome: An update on diagnosis and management

March 2026 in “Cleveland Clinic Journal of Medicine”

PCOS diagnosis and management have improved with new guidelines for personalized care.

research Serum irisin level in patients with acne vulgaris

January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences”

Patients with acne vulgaris have lower serum irisin levels.

The Effects of Probiotics, Prebiotics, and Synbiotics Supplementation on Polycystic Ovary Syndrome: An Umbrella Review of Meta-Analyses of Randomized Controlled Trials

research The effects of pro-, pre- and synbiotics supplementation on polycystic ovary syndrome: an umbrella review of meta-analyses of randomized controlled trials

September 2022 in “Research Square (Research Square)”

Probiotics and synbiotics may help with PCOS symptoms, but more research is needed.

research Identification of neprilysin as a potential target of arteannuin using computational drug repositioning

January 2017 in “Brazilian Journal of Pharmaceutical Sciences”

Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.