research Retinoic-Acid-Related Orphan Receptor Alpha Is Involved in the Regulation of the Cytoskeleton of Hair Follicle Stem Cells
RORA affects hair follicle stem cells' structure and movement, potentially helping treat hair loss.
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research Human Fibroblast‐Derived Matrix Hydrogel Accelerates Regenerative Wound Remodeling Through the Interactions with Macrophages
A new hydrogel made from human cells improves wound healing by working with immune cells to promote repair.
research Epithelial cell migration on laminins
Collagen XVII and CD151 affect cell movement, with CD151 inhibiting migration when bound to integrins.
research A cell polarity protein, aPKCλ, is essential for maintaining hair follicle stem cell quiescence and hair follicle regeneration
The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.
research Animal models of human skin disease
Mutations in certain skin proteins cause severe skin issues, while others have limited effects, highlighting the need to understand these proteins for better treatments.
research Smooth muscle cell expression of a constitutive active form of human Profilin1 accelerates cutaneous wound repair
Profilin1 speeds up wound healing.
research Histochemical studies on cutaneous stem cells in human fetal skin
Basal layer skin cells help form the epidermis and hair follicles.
research Stem Cells in Nonmelanoma Skin Cancer
Stem cells play a key role in nonmelanoma skin cancers, with different origins and genetic changes linked to basal and squamous cell carcinomas.
research Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34
CD34 is a marker for isolating stem-like cells in mouse hair follicles.
research Manipulation of stem cell proliferation and lineage commitment:visualisation of label-retaining cells in wholemounts of mouse epidermis
Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
research The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche
Nephronectin helps attach muscle cells to hair follicles.
research Location and phenotype of human adult keratinocyte stem cells of the skin
Stem cells are in deep skin layers, while differentiating cells are in shallow layers.
research Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats
Key genes and pathways crucial for hair follicle development in cashmere goats were identified, aiding fleece production improvement.
research Characterization and Localization of Side Population Cells in Mouse Skin
Mouse skin has special cells in the epidermis that decrease with age and are linked to keratinocyte stem cells.
research Changing Patterns of Localization of Putative Stem Cells in Developing Human Hair Follicles
Stem cells in developing hair follicles move to specific areas as they mature.
research A Review: The Location, Molecular Characterisation and Multipotency of Hair Follicle Epidermal Stem Cells
Hair follicle stem cells are mainly in the bulge region and can help repair skin and form hair and glands, but more research is needed to fully understand them.
research 25 Years of Epidermal Stem Cell Research
Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
research Epidermal and Hair Follicle Progenitor Cells Express Melanoma-Associated Chondroitin Sulfate Proteoglycan Core Protein
MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.
research Immunofluorescence analysis of the basement membrane zone components in human anagen hair follicles
The upper hair follicle is stable, while the lower part allows movement during hair growth.
research Bulge cells of human hair follicles: segregation, cultivation and properties
Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
research Transient expression of keratin 19 is induced in originally negative interfollicular epidermal cells by adhesion of suspended cells.
Keratin 19 expression in certain skin cells is temporary and not a reliable stem cell marker.
research Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations
Increased Stat3 activity reduces hair follicle stem cells and boosts other stem/progenitor cells.
research Corneal epithelial‐like transdifferentiation of hair follicle stem cells is mediated by pax6 and β‐catenin/Lef‐1
Hair follicle stem cells can become corneal-like cells with the help of pax6.
research ADSCs inhibit photoaging‐ and photocarcinogenesis‐related inflammatory responses and extracellular matrix degradation
ADSCs help protect skin from UV damage and aging.
research Expansion of the spectrum of ITGB6-related disorders to adolescent alopecia, dentogingival abnormalities and intellectual disability
A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.
research Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis
ABCG2 protein marks stem-like skin cells in human epidermis.
research Behavior of Human Foreskin Keratinocytes Expressing a Hair Follicle Stem Cell Marker CD200
CD200 is not a reliable marker for identifying stem cells in all skin types.
research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle
Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
research In-vivo dedifferentiation of keratinocytes to epidermal stem cells
Keratinocytes might turn into stem cells, but more research is needed to confirm this.
research Two’s Company, Three’s a Hair Cycle? hfDSCs Join the Hair Germ–Dermal Papilla Regulatory Interface
Hair follicle dermal stem cells help control hair growth timing by regulating signals at the hair germ–dermal papilla interface.