research Field melanin mapping of the hairless scalp
The study found a specific pattern of uneven melanin distribution on balding scalps that could help understand skin diseases caused by light exposure.
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research A Review of the Impact of Calorie Restriction on Stem Cell Potency
Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.
research Trichotillomania
Trichotillomania is a disorder where people compulsively pull out their hair, treated with drugs and behavior therapy.
research A neuroendocrinological perspective on human hair follicle pigmentation
Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
research Expression of epidermal keratins and filaggrin during human fetal skin development.
Keratins and filaggrin change as fetal skin develops, marking key stages of skin formation.
research Hidradenitis Suppurativa Tunnels: Unveiling a Unique Disease Entity
Hidradenitis suppurativa tunnels worsen the disease and often need surgery because current treatments are not very effective.
research Organ Culture of Developing Mouse Skin and Its Application for Molecular Mechanistic Studies of Morphogenesis
Epidermal growth factor stops hair follicle formation in developing mouse skin.
research The Human Hair Follicle: A Reservoir of CD40+ B7-Deficient Langerhans Cells that Repopulate Epidermis After UVB Exposure
Hair follicles help skin immune recovery after UVB exposure.
research Exact, time-independent estimation of clone size distributions in normal and mutated cells
A new method accurately estimates clone sizes in cells without considering time.
research Role of the bone morphogenetic protein signalling in skin carcinogenesis. Effect of transgenic overexpression of BMP antognist Noggin on skin tumour development; molecular mechanisms underlying tumour suppressive role of the BMP signalling in skin.
BMP signaling helps prevent skin tumors by blocking cancer-promoting pathways.
research Runx3 is involved in hair shape determination
Runx3 helps determine hair shape.
research Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle
Mutant MK6a transgenes in mice cause blistering, hair loss, and potential human alopecia.
research Histochemistry of the porcine pilosebaceous unit
Porcine and human pilosebaceous units are very similar.
research c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
research Immunofluorescence analysis of the basement membrane zone components in human anagen hair follicles
The upper hair follicle is stable, while the lower part allows movement during hair growth.
research Selective Expression of Calcium-Binding Proteins S100A8 and S100A9 at Distinct Sites of Hair Follicles
S100A8 and S100A9 proteins help form hair shafts during growth.
research Development and Maintenance of Epidermal Stem Cells in Skin Adnexa
Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.
research Ontogeny of Skin Stem Cells and Molecular Underpinnings
Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.
research Eyes open on stem cells
Stem cells in the cornea show unexpected flexibility and have important implications for medicine.
research Integrating stem cell biology and organoid technology for skin regenerative therapies
Combining stem cells and organoids could improve skin regeneration treatments.
research CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia
CDK4/6 inhibitors can protect hair cells from chemotherapy damage.
research Does fat get you skinny?
Fat may help skin health and repair, but more research is needed.
research The remarkable legacy of the K6/ODC mouse: mechanisms of polyamine-promoted tumorigenesis revealed
Polyamines are crucial for skin tumor development, and inhibiting them can prevent tumors.
research Dermal fibroblasts: the terminology, heterogeneity of subpopulations and common properties
Dermal fibroblasts have at least three distinct types, each with unique roles in skin structure and hair development.
research Abstract 2559: Targeting mTORC1 may provide selectivity for inhibiting proliferation of hair follicle stem/progenitor cells during tumor promotion
Blocking mTORC1 may help prevent skin cancer by stopping the growth of certain skin stem cells.
research ‘Neurotrophology’ of the hair follicle: neurotrophins act as auto‐ and paracrine growth factors and immunomodulators
Neurotrophins are important for hair growth and response to stress.
research Cutaneous neuroimmunology – lessons from the hair follicle
Stress and certain chemicals affect hair growth by interacting with the immune and nervous systems.
research Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways
Noggin promotes skin tumors by activating certain cell signaling pathways.
research Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle
Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.
research Understanding Melanocyte Stem Cells for Disease Modeling and Regenerative Medicine Applications
Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.