research Congenital hair loss disorders: Rare, but not too rare
Some hair loss disorders are caused by genetic mutations affecting hair growth.
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research Keratin network modifications lead to the mechanical stiffening of the hair follicle fiber
Changes in keratin make hair follicles stiffer.
research Cysteine Prevents the Reduction in Keratin Synthesis Induced by Iron Deficiency in Human Keratinocytes
Cysteine helps maintain keratin production in skin cells even when iron is low.
research A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats
A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.
research Therapeutic Applications of Nanoemulsion Based Drug Delivery Systems: A Review of Patents in Last Two Decades
Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.
research Stem cell factor/c-Kit signalling in normal and androgenetic alopecia hair follicles
SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
research Hypertrichosis induced by latanoprost
Latanoprost, a glaucoma medication, caused excessive eyelid hair growth in many patients.
research TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia
The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
research Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments
Hair proteins have weak spots in their α-helical segments.
research Photobiomodulation devices for hair regrowth and wound healing: a therapy full of promise but a literature full of confusion
Photobiomodulation may help with hair growth and wound healing, but research is inconsistent and needs better quality studies.
research Chapter 7 Reproductive Dysfunction in Women with Epilepsy
Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.
research The advantages of hair follicle pluripotent stem cells over embryonic stem cells and induced pluripotent stem cells for regenerative medicine
Hair follicle stem cells are a practical and ethical option for nerve repair in regenerative medicine.
research Hair removal using an Nd: YAG laser system.
Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.
research Quantitative assessment of 2% topical minoxidil in the treatment of male pattern baldness
The study tested a hair treatment and found it can help grow hair, but won't stop baldness. It's safe and works well, but needs more testing.
research Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research The structure of the “amorphous” matrix of keratins
Human hair keratin fibers have a detailed nano-scale structure that changes with different conditions.
research Modeling of chronic radiation-induced cystitis in mice
Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
research Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 (RSK1) in a Growth- and Stress-dependent Fashion
Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.
research Follicular streamers (stelae) in scarring and non-scarring alopecia
Hair root sheaths are more common in non-scarring hair loss and help diagnose the type of hair loss.
research KERATINS AND SKIN DISORDERS
Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
research Fabrication of a 3D hair follicle‐like hydrogel by soft lithography
Researchers created a 3D hydrogel that mimics human hair follicles, which may help with hair loss treatments.
research Relationship between betacoronaviruses and the endocrine system: a new key to understand the COVID-19 pandemic—A comprehensive review
Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.
research Regenerative medicine and hair loss: how hair follicle culture has advanced our understanding of treatment options for androgenetic alopecia
Hair follicle culture helps develop new treatments for hair loss.
research Major depletion of SOX2+ stem cells in the adult pituitary is not restored which does not affect hormonal cell homeostasis and remodelling
The pituitary gland functions normally even after losing most SOX2+ stem cells.
research Androgenetic alopecia
Hair loss from genetics and hormones can be treated with drugs or surgery.
research Interventions for female pattern hair loss
Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.
research A Multi-Technique Approach to the Study of Structural Stability and Desolvation of Two Unusual Channel Hydrate Solvates of Finasteride
Desolvation of finasteride depends on environment and technique.
research Opening new horizons in regenerative dermatology using platelet‐based autologous therapies
Platelet-based therapies using a patient's own blood show promise for skin and hair regeneration but require more research for confirmation.
research Getting under the skin: what is the potential of the transfollicular route in drug delivery?
The transfollicular route shows promise for noninvasive, targeted drug delivery but needs more research.
research The proteomic profile of hair damage
Bleaching hair damages protein structure, especially keratin, leading to weakened hair.