23 citations
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March 1958 in “JNCI Journal of the National Cancer Institute” Male-to-female skin grafts in mice are rejected due to sex-linked antigens.
60 citations
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November 2009 in “General and Comparative Endocrinology” Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
January 2026 in “JCEM Case Reports” Genetics may play a significant role in gender dysphoria.
5 citations
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January 2023 in “Fertility and sterility” Doctors are preparing to potentially perform uterus transplants in transgender women, considering technical, hormonal, and ethical factors.
January 2026 in “Immunological Reviews” Females generally have stronger immune responses than males due to the X chromosome.
1 citations
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May 2018 in “Clinical chemistry” The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.
September 2021 in “Physiology News” Conditions affecting sex development show that sexual diversity is a natural part of human variation.
October 2023 in “Urologie in der Praxis” Primary care providers should understand Geschlechtsinkongruenz to offer better care for transitioning individuals.
30 citations
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December 1996 in “Journal of Investigative Dermatology” June 2020 in “Zenodo (CERN European Organization for Nuclear Research)” Robertsonian translocation can cause recurrent miscarriages.
1 citations
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January 2016 in “Medicinski glasnik Specijalne bolnice za bolesti štitaste žlezde i bolesti metabolizma” Most 46XX CAH patients have female identity, but a few identify as male and may need treatment and surgery.
29 citations
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May 2013 in “Andrologia” Cross-sex hormone treatment in transsexual individuals helps understand how sex hormones affect diseases like heart disease and diabetes.
83 citations
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August 2018 in “BJOG” Uterine transplants for transgender women are feasible but need more research.
January 2025 in “Case Reports in Genetics” A rare gene variant causes sexual development issues in siblings, needing personalized treatment.
4 citations
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August 2021 in “Pediatrics in review” DSDs are birth conditions causing unusual sex development, managed with personalized care and sometimes surgery, but still lack a standard treatment approach.
51 citations
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August 2012 in “Differentiation” Mouse genital development depends on male or female hormones for specific features.
46 citations
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December 1992 in “The Journal of Steroid Biochemistry and Molecular Biology” Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.
September 2020 in “Journal of Health, Medicine and Nursing” A 10-year-old boy with abnormal genital development had surgery and tests to find the cause and plan treatment.
December 2022 in “Brazilian Journal of Health Review” Patients with Complete Androgen Insensitivity Syndrome need psychological support and multidisciplinary care for complex treatment decisions.
Mental health and hair loss are linked, and treating both can improve well-being.
10 citations
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September 1997 in “Molecular carcinogenesis” Mirex seems to promote a unique group of skin cells different from those affected by another tumor promoter, TPA.
April 2019 in “Journal of the Endocrine Society” Mosaic Klinefelter syndrome can affect male fertility and may be missed in routine tests.
The white wax scale insect's genome shows that complete metamorphosis evolved earlier than thought and highlights differences in male and female development.
78 citations
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August 1996 in “The Journal of Clinical Endocrinology & Metabolism” The same gene mutation can cause different symptoms in family members.
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April 2010 in “Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology” The piRNA pathway genes are crucial in early development and may influence sex differentiation through hormone regulation.
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November 2020 in “UNC Libraries” A point mutation in the androgen receptor gene causes complete androgen insensitivity.
Long non-coding RNA Xist plays a key role in sex bias in lupus and rheumatoid arthritis, especially in females.
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March 2006 in “TSpace”
210 citations
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November 2015 in “The Lancet HIV” PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.
August 2022 in “MEDICINUS” A 22-year-old homosexual man was diagnosed with secondary syphilis, genital warts, and HIV, highlighting the high STI risk in men who have sex with men.