research Iatrogen male infertility
Medical treatments like chemotherapy and radiotherapy can harm sperm production, so freezing sperm before treatment is important for men who want children later.
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research Effects of depot medroxyprogesterone acetate, the copper IUD and the levonorgestrel implant on testosterone, sex hormone binding globulin and free testosterone levels: ancillary study of the ECHO randomized clinical trial
The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.
research Efficacy and safety of intradermal injection of some therapeutics in treatment of androgenetic alopecia: Comparative study
Intradermal injections might work better for common hair loss than other treatments.
research Phosphodiesterase inhibitors used in androgenic alopecia as a possible risk factor for testicular tumor
research Changes of sex hormone levels in male acne patients with normal serum testosterone and effect of antiandrogen therapy
Finasteride with lifestyle changes effectively treats acne in males by improving hormone levels and reducing recurrence.
research DHT deficiency perturbs the integrity of the rat seminiferous epithelium by disrupting tight and adherens junctions
DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.
research News & Notes
Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.
research Clinical Evaluation of Intralesional Triamcinolone
Different doses of triamcinolone injections work equally well for skin conditions.
research Paradigm Shift in the Concept of Hormonal Milieu of Prostate Cancer
Prostate cancer risk is not linked to blood testosterone levels.
research Intradermal Injection in Balding Region Versus Intramuscular Injection in Surrounding Muscles: A Split-Scalp, Randomized Trial on BoNT for Androgenetic Alopecia
Intramuscular injections improved hair density more than intradermal injections for treating hair loss.
research An ovarian Leydig cell tumor of ultrasound negative in a postmenopausal woman with hirsutism and hyperandrogenism
A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.
research A case of hyperpigmentation and acanthosis nigricans by testosterone injections
Testosterone injections can cause skin darkening and thickening.
research Diagnostic Challenges in Ovarian Hyperthecosis: Clinical Presentation with Subdiagnostic Testosterone Levels
Ovarian hyperthecosis can cause symptoms even with normal testosterone levels, and surgery can improve these symptoms.
research Suppression of spermatogenesis with desogestrel and testosterone pellets is not enhanced by addition of finasteride.
research Intralesional Triamcinolone Acetonide Versus Topical Betamethasone Valearate in the Management of Localized Alopecia Areata.
Intralesional triamcinolone is more effective than topical betamethasone for treating localized alopecia areata.
research The stimulation of hair growth in the flank organs of female hamsters by subcutaneous testosterone propionate and its inhibition by topical cyproterone acetate: dose-response studies
Testosterone increases hamster hair growth; cyproterone acetate reduces it.
research SAT-288 Successful Virilization of a PAIS Patient with a Missense Mutation In The Ligand-binding Domain Of The Androgen Receptor with Combined High-dose Testosterone and Aromatase Inhibitor
A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
research Letter to the Editor on “COVID-19 Infection in Men on Testosterone Replacement Therapy”
The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.
research The Effects of Oral 5-alpha Reductase Inhibitors on Penile Intracavernosal Pressures and Penile Morphology in Rat Model.
Oral finasteride and dutasteride may negatively affect erectile function in rats.
research Diagnosis of an indistinct Leydig cell tumor by positron emission tomography-computed tomography
A PET-CT scan successfully located a hard-to-find Leydig cell tumor in a woman with hormonal symptoms.
research Androgen receptor–mediated inhibition of cutaneous wound healing
Lowering testosterone speeds up wound healing in male mice.
research Dihydrotestosterone Stimulates 5a-Reductase Activity in Pubic Skin Fibroblasts*
Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
research The place of intralesional steroid therapy in dermatology
Intralesional steroid therapy is useful for treating various skin conditions.
research Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood
CTIP2 may help in skin development and maintenance.
research [Genetic dissection of retinoic acid function in epidermis physiology].
Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.
research Hair disorder in dr. Cipto Mangunkusumo cosmetic dermatology and venereology outpatient clinic of Jakarta, Indonesia: A socio-demographic and clinical evaluation
Most hair disorder patients at the clinic were young adult males, with alopecia areata being the most common condition.
research Diagnosis dan Farmakoterapi Penyakit Paru Obstruktif Kronis
Chronic obstructive pulmonary disease (COPD) is managed with personalized medication to ease symptoms and improve life quality.
research Tata Laksana Refluks Gastroesofageal pada Anak
Proper management of GER in children is crucial for effective treatment and referrals.
research REVIEW: THE POTENTIAL OF HERBAL PLANTS AS ANTI-ALOPECIA MEDICINES
Herbal plants may help treat hair loss with fewer side effects than synthetic drugs.
research UJI STABILITAS FISIK FORMULASI SEDIAAN HAIR TONIC HERBAL BUAH MENTIMUN (Cucumis Sativus L) SEBAGAI PERAWATAN RAMBUT
Cucumber hair tonic formulations are stable and may help with hair loss.