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A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.

Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

DA liposomes with chloramphenicol effectively target hair follicles and combat MRSA with minimal skin toxicity.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

Human hair keratin helps repair nerve damage in rats.

A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.

The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.

High doses of finasteride cause cell growth and tumors in mice.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.

Keratin fibrils in hair form and stop growing at specific points in the follicle.

Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.