22 citations
,
September 2001 in “Journal of Investigative Dermatology” S100A8 and S100A9 proteins help form hair shafts during growth.
10 citations
,
June 2013 in “International Journal for Vitamin and Nutrition Research” High hair calcium levels are linked to low calcium intake and low bone density.
April 2024 in “Archives of toxicology” Certain substances can protect against ear damage from some antibiotics in zebrafish.
2 citations
,
September 2004 in “Experimental Dermatology” Desmosomal adhesion is essential for healthy skin structure and function.
83 citations
,
December 2001 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
69 citations
,
March 2003 in “Journal of Experimental Botany” Sodium chloride slows root hair growth by altering calcium levels, not pH.
6 citations
,
October 2022 in “Frontiers in Physiology” Calcium channels are vital for normal skin function and their dysfunction can lead to skin issues.
277 citations
,
July 2002 in “Molecular Endocrinology” Removing part of the vitamin D receptor stops vitamin D from working properly.
105 citations
,
May 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Activating TRPV3 stops human hair growth.
93 citations
,
March 2017 in “Molecular Plant” CNGC14 is crucial for calcium entry needed for root hair growth in plants.
68 citations
,
June 2005 in “Expert Opinion on Therapeutic Targets” Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
46 citations
,
May 2003 in “Mechanisms of Development” Increasing calcium sensing receptor speeds up skin and hair development in mice.
27 citations
,
June 2013 in “Genes & development” Cav1.2 affects hair growth and could be a target for hair loss treatments.
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Prss53 affects hair shape and bone development in rabbits.
506 citations
,
January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
95 citations
,
February 2019 in “The New England Journal of Medicine” Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.
37 citations
,
March 2018 in “Trends in Plant Science” pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.
19 citations
,
February 2018 in “Nutrients” Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.
13 citations
,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
11 citations
,
September 1999 in “Biological Trace Element Research” Mineral deficiencies in pregnant women can be improved with proper supplementation.
10 citations
,
May 2019 in “International Journal of Environmental Research and Public Health” Finasteride may cause kidney damage.
7 citations
,
January 2017 in “Journal of cosmetology & trichology” Good nutrition is crucial for healthy hair and can help with hair loss without medication.
1 citations
,
October 2025 in “International Journal of Nanomedicine” Exosomes could revolutionize skin disease treatment and healing.
1 citations
,
January 2024 in “International journal of molecular sciences” TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.
1 citations
,
January 2024 in “Theranostics” Exosomes show promise for future tissue regeneration.
February 2026 in “Plastic and Aesthetic Research” Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.
May 2025 in “Science Advances” PIEZO1 helps keep hair follicle stem cells inactive, affecting hair growth.
47 citations
,
March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
42 citations
,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
3 citations
,
January 1991 in “Toxicology in Vitro” Hair follicle cultures are effective for studying cell communication and testing chemicals.