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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

TLR-targeted therapies show promise in cancer treatment by helping destroy tumors.

Human hair follicles contain a complex network of prostanoid receptors that may influence hair growth.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

CI-1033 causes skin lesions in rats, similar to humans, due to EGF receptor inhibition.

Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.

ROR2 is essential for hair follicle stem cell renewal and maintenance.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

Transferrin receptor expression increases iron in mouse skin cells without causing damage.

Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.

17β-estradiol lowers polyamine oxidase levels in breast cancer cells through estrogen receptor 2.

Targeting TRP channels may help reduce excessive scarring.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

Adenosine receptors could be promising targets for treating inflammatory skin diseases like psoriasis.

High TNF-α levels may increase hair loss risk after PRP therapy.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

TRPV3 channels are involved in skin processes and are affected by shear stress, influencing itch and mechanotransduction.

Chromosomal differences affect how muscle cells respond to testosterone.

Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.

Neurohormones help control skin health and could treat skin disorders.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.

Leptin helps start the growth phase of hair.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Adding dutasteride to therapy may improve treatment for advanced salivary duct cancer.

CK 5/6 expression in breast cancer is linked to negative hormone receptor status and higher tumor grade.

ROR-alpha may increase the growth of certain breast cancer cells by boosting aromatase, which could affect breast cancer prognosis.