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Deletion of Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2 in FoxD1-Lineage Mesenchymal Cells Leads to Congenital Truncal Alopecia

research Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.

research Cornification

September 2018

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

research Adipose-Derived Stem Cells and Their Secretory Factors for Skin Aging and Hair Loss

January 2015 in “Springer eBooks”

Fat-derived stem cells and their secretions show promise for treating skin aging and hair loss.

research The role of integrin alphavbeta6 in impaired wound healing and hair follicle regeneration

January 2010

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

research The Pathogenesis of Primary Cicatricial Alopecias

150 citations , October 2010 in “The American Journal of Pathology”

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Label Retaining Cells with Myoepithelial Characteristics from the Proximal Acinar Region Define Stem Cells in the Sweat Gland

research Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland

36 citations , September 2013 in “PLoS ONE”

Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.

A Bald Statement: Current Approaches to Manipulate Miniaturization Focus Only on Promoting Hair Growth

research A bald statement - Current approaches to manipulate miniaturisation focus only on promoting hair growth

30 citations , May 2018 in “Experimental Dermatology”

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

The Topography of Fibrous Scaffolds Modulates the Paracrine Function of Adipose-Derived Mesenchymal Stem Cells in the Regeneration of Skin Tissues

research The topography of fibrous scaffolds modulates the paracrine function of Ad-MSCs in the regeneration of skin tissues

24 citations , January 2019 in “Biomaterials Science”

The shape of fibrous scaffolds can improve how stem cells help heal skin.

CRISPR/Cas9-Mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen

research CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen

13 citations , March 2020 in “Genes”

Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.

research Molecular and spatial design of early skin development

3 citations , December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

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