6 citations
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November 2004 in “Bioorganic & Medicinal Chemistry Letters” Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.
Finasteride significantly reduced sperm production and caused testicular atrophy in hamsters.
8 citations
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January 2012 in “General and Comparative Endocrinology” 5α-Reductase helps regulate hormone action in toad testes, especially during breeding season.
22 citations
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January 2001 in “Chemical & Pharmaceutical Bulletin” Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
3 citations
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March 2016 in “Medicinal Chemistry Research” Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.
24 citations
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March 2011 in “British Journal of Dermatology” Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.
24 citations
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October 2012 in “The International Journal of Biochemistry & Cell Biology” Testosterone protects female heart cells from stress by activating estrogen receptors.
1 citations
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January 2003 in “Chinese Journal of Pharmaceuticals” A new method to make Finasteride is more cost-effective and yields 16%.
June 1995 in “International Journal of Gynecology & Obstetrics” Women with hair loss have higher androgen levels, while men with early balding have altered androgen ratios.
April 2011 in “Cancer Research” 20(S)-Protopanaxadiol-aglycone may help prevent and treat prostate cancer by reducing androgen receptor activity.
4 citations
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April 1999 in “Dermatologic Clinics” Androgens, like DHT, affect hair growth and treatments like finasteride may help.
September 2024 in “Medicine theory and practice” A young girl's hyperandrogenism was caused by an adrenocortical adenoma, diagnosed and treated through detailed evaluations.
2 citations
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March 2012 in “Nature Reviews Endocrinology” The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.
May 2024 in “Skin research and technology” Certain metabolites can either protect against or increase the risk of hair loss.
1 citations
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May 2025 in “The Journal of Phytopharmacology” Phytoandrogens from plants may help treat low testosterone naturally.
May 2022 in “Reactions Weekly”
June 2023 in “Oriental Journal of Chemistry/Oriental journal of chemistry” New compounds may help treat prostate cancer by reducing cell growth.
20 citations
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January 2007 in “Fertility and Sterility” A woman developed male traits from accidental contact with her husband's testosterone gel.
124 citations
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September 1992 in “Endocrinology” The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
14 citations
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December 2013 in “Experimental Dermatology” The T-zone on the face has more androgen receptors and produces more oil than the U-zone.
January 2000 in “Hair and its disorders: biology, pathology and management, 2000, ISBN 1853177997, págs. 137-152”
April 2017 in “Journal of Investigative Dermatology” Found new possible treatments for hair loss.
48 citations
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February 2006 in “Molecular and Cellular Endocrinology” 5α-reductase inhibitors may reduce male fertility and could be used for male contraception.
1 citations
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April 2015 in “The FASEB Journal” Blocking androgens in male rats increased estrogen and made them more active.
1 citations
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July 2022 in “International journal of dermatology and clinical research” Understanding androgen receptors, oxidative stress, and inflammation is key to developing better skin disease treatments.
21 citations
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August 2001 in “PubMed” Finasteride helps hair growth by reducing DHT levels.
12 citations
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June 2013 in “The Prostate” Dutasteride and finasteride affect different cell types differently.
September 1978 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”
10 citations
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December 1996 in “Fertility and Sterility” Women with acne have lower levels of a specific hormone marker than women without acne.