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January 2004 in “Adelaide Research & Scholarship (AR&S) (University of Adelaide)” SPARC likely aids in tissue remodeling during the hair cycle, not in starting new hair growth phases.
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K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.
July 2025 in “Journal of Investigative Dermatology” Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.
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The trichohyalin gene is located at chromosomal region 1q21 with other skin-related protein genes.
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