research D2-40 Expression in Primary Scarring and Nonscarring Alopecia
Most people with scarring and nonscarring hair loss show similar D2-40 levels, but some with scarring hair loss have higher levels.
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research Clinicopathologic study of 90 cases of trichofolliculoma
Trichofolliculoma is a unique benign tumor mainly affecting middle-aged adults' faces, often misdiagnosed without histopathology.
research Preferential Crosstalk between Perifollicular Capillary Vessels and Dermal Papilla Cells during Hair Cycling Homeostasis
Enhancing blood vessel interactions with hair cells may help treat hair loss and skin aging.
research [Hirsutism].
Hirsutism is excessive male-pattern hair growth mainly caused by ovarian hormones, and severe cases may require costly treatment with side effects.
research Δ5-3β-Hydroxysteroid Dehydrogenase Activity in Sebaceous Glands of Scalp in Male-Pattern Baldness
research Perifollicular Fibrosis in Androgenetic Alopecia
Perifollicular fibrosis hinders hair regrowth in androgenetic alopecia, and new treatments targeting fibrosis are needed.
research Bound on the Risk for M-SVMs
The enzyme system in hair follicles is similar to the liver's and is inhibited by certain substances.
research Human scalp hair: Modulation by various factors and hormones do estrogens inhibit or stimulate—A perplexing perspective
The effects of estrogen on human scalp hair growth are unclear and need more research.
research 862 Defining the molecular signature of the hair follicle dermal sheath and its functional requirement for hair cycle progression during catagen
The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.
research The Modulation of Aromatase and Estrogen Receptor Alpha in Cultured Human Dermal Papilla Cells by Dexamethasone: A Novel Mechanism for Selective Action of Estrogen via Estrogen Receptor Beta?
Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.
research 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts
Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
research Guides: Open Access: Learn More
Vitamin D receptor is essential for preventing hair loss by regulating hair cycle stages.
research Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin
Follistatin helps hair growth and cycling, while activin prevents it.
research Serum elevation of dehydroepiandrosterone sulfate associated with male pattern baldness in young men
High DHEA-S levels may cause hair loss in young men.
research Finasteride in the treatment of hirsutism: new therapeutic perspectives
Finasteride effectively treats hirsutism in women, but more research needed for long-term results.
research 1494 Dual effects of HA-iMSC-exosomes in human follicle dermal papilla cells (HFDPC) on androgenic alopecia in vitro model
Exosomes from certain stem cells can fight hair loss by promoting hair growth and maintaining the growth phase of hair.
research Pharmacodynamic modeling of finasteride, a 5 alpha-reductase inhibitor.
Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.
research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture
research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture
research Comparative analysis of 3D and 2D cell-culturing methods in hair follicle spheroid morphogenesis and drug responsiveness
3D cultures respond better to minoxidil, while 2D cultures respond better to DHT.
research TSH is a novel neuroendocrine regulator of selected keratins in the human hair follicle
TSH influences keratin expression in human hair follicles.
research withdrawn
Dutasteride works better than finasteride for hair growth with similar side effects.
research Dopamine is a novel, direct inducer of catagen in human scalp hair folliclesin vitro
Dopamine stops hair growth and pigment production in human scalp hair follicles.
research 1α,25-Dihydroxyvitamin D3 Modulates the Hair-Inductive Capacity of Dermal Papilla Cells: Therapeutic Potential for Hair Regeneration
Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.
research Dynamic expression of the zinc-finger transcription factor Trps1 during hair follicle morphogenesis and cycling
Trps1 plays a key role in hair follicle development and cycling.
research Safety aspects of androgen treatment with 5α-dihydrotestosterone
DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
research Hirsutism, its pathogenesis
Hirsutism in females is caused by high male hormones or sensitive hair follicles.
research Data Sheet 1_Angiopoietin-1 induces survival and proliferation of hair follicle dermal papilla cells through integrin α5β1 signaling.pdf
Angiopoietin-1 helps hair follicle cells survive and grow, potentially treating hair loss.
research Trypsin‐induced follicular papilla apoptosis results in delayed hair growth and pigmentation
Trypsin slows hair growth and affects color by causing cell death in hair follicles.
research Hypoxia inducible factor-1α promotes trichogenic gene expression in human dermal papilla cells
HIF-1α is important for hair growth and could be a treatment target for hair loss.