August 2025 in “Journal of Investigative Dermatology” Elevated luteinizing hormone contributes to female-pattern hair loss, and blocking certain channels may help prevent it.
28 citations
,
January 2009 in “Cellular & Molecular Biology Letters” DHT deficiency increases iNOS expression in rat testis and epididymis.
11 citations
,
June 2005 in “Veterinary Dermatology” Canine hair follicle cells convert progesterone into various metabolites, mainly cortisol.
January 1986 in “Journal of Steroid Biochemistry” Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.
30 citations
,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” The lipid in human hair follicles acts as a barrier, similar to the skin's lipid layer.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Taking finasteride daily can effectively and safely increase hair density and thickness for women with hair loss.
82 citations
,
January 2000 in “Hormone Research in Paediatrics” DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
30 citations
,
May 2018 in “Experimental Dermatology” The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
13 citations
,
November 2010 in “Experimental Dermatology” Vitamin C derivative reduces hair loss-related protein in cells.
January 2026 in “Non-coding RNA Research” Exosomal miRNA-218-5p promotes hair growth and development.
154 citations
,
October 1996 in “Proceedings of the National Academy of Sciences of the United States of America” Estrogen affects hair growth and skin cell multiplication.
58 citations
,
June 1987 in “Archives of Dermatological Research” EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.
12 citations
,
June 2017 in “Dermatologic therapy” Higher concentrations of dithranol can help regrow hair in severe alopecia areata.
January 2022 in “Figshare” Exosomes from dermal papilla cells help hair stem cells grow through a specific signaling pathway.
3 citations
,
April 2010 in “The American Journal of Dermatopathology” Most people with scarring and nonscarring hair loss show similar D2-40 levels, but some with scarring hair loss have higher levels.
19 citations
,
September 2016 in “Journal of the European Academy of Dermatology and Venereology” Trichofolliculoma is a unique benign tumor mainly affecting middle-aged adults' faces, often misdiagnosed without histopathology.
October 2025 in “Research Square (Research Square)” Enhancing blood vessel interactions with hair cells may help treat hair loss and skin aging.
September 1976 in “PubMed” Hirsutism is excessive male-pattern hair growth mainly caused by ovarian hormones, and severe cases may require costly treatment with side effects.
69 citations
,
August 1988 in “Journal of Investigative Dermatology”
April 2026 in “Brazilian Journal of Hair Health” Perifollicular fibrosis hinders hair regrowth in androgenetic alopecia, and new treatments targeting fibrosis are needed.
January 2002 in “HAL (Le Centre pour la Communication Scientifique Directe)” The enzyme system in hair follicles is similar to the liver's and is inhibited by certain substances.
3 citations
,
February 2019 in “Journal of Cosmetic Dermatology” The effects of estrogen on human scalp hair growth are unclear and need more research.
April 2017 in “Journal of Investigative Dermatology” The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.
65 citations
,
May 2006 in “Journal of Investigative Dermatology” Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.
June 2020 in “Journal of Investigative Dermatology” Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
81 citations
,
January 2003 in “The FASEB Journal” Follistatin helps hair growth and cycling, while activin prevents it.
January 2010 in “Life Science Alliance” Vitamin D receptor is essential for preventing hair loss by regulating hair cycle stages.
52 citations
,
March 1987 in “Journal of the American Academy of Dermatology” High DHEA-S levels may cause hair loss in young men.
50 citations
,
July 1996 in “Fertility and Sterility” Finasteride effectively treats hirsutism in women, but more research needed for long-term results.
April 2023 in “Journal of Investigative Dermatology” Exosomes from certain stem cells can fight hair loss by promoting hair growth and maintaining the growth phase of hair.