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In Vivo Evaluation of the Efficacy, Toxicity, and Biodistribution of PLGA-DMSA Nanoparticles Loaded with Itraconazole for Treatment of Paracoccidioidomycosis

research In vivo evaluation of the efficacy, toxicity and biodistribution of PLGA-DMSA nanoparticles loaded with itraconazole for treatment of paracoccidioidomycosis

8 citations , March 2018 in “Journal of Drug Delivery Science and Technology”

Itraconazole-loaded nanoparticles are more effective and less toxic for treating fungal infections than conventional oral itraconazole.

research Metabolite screening of aromatic amine hair dyes usingin vitrohepatic models

16 citations , October 2009 in “Xenobiotica”

The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.

research Metal-Chelation-Assisted Deposition of Polydopamine on Human Hair: A Ready-to-Use Eumelanin-Based Hair Dyeing Methodology

63 citations , February 2017 in “ACS biomaterials science & engineering”

Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.

research α‐Difluoromethylornithine, a polyamine inhibitor: its potential role in controlling hair growth and in cancer treatment and chemo‐prevention

9 citations , April 2006 in “International Journal of Dermatology”

DFMO may help control hair growth and treat cancer.

research Long-term toxicity studies on oxidation hair dyes

79 citations , January 1975 in “Food and Cosmetics Toxicology”

The hair dye formulations tested did not cause long-term toxicity or cancer in mice.

research Preliminary toxicity profile of arotinoids SMR-2 and SMR-6 in male B6D2F1 mice*1

15 citations , May 1987 in “Fundamental and applied toxicology”

SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe side effects.

research Promotion of Skin Carcinogenesis by Dimethylarsinic Acid in Keratin (K6)/ODC Transgenic Mice

48 citations , June 2000 in “Japanese Journal of Cancer Research”

Dimethylarsinic acid speeds up skin tumor growth in certain mice.

research 267 Single- and multiple-ascending dose studies of DS-2325a, a KLK5 inhibitor for the treatment of Netherton syndrome

July 2024 in “Journal of Investigative Dermatology”

DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.

research [An immunohistochemical study on the normal human anagen hair and hair follicle using anti-hair keratin monoclonal antibodies (HKN-5, HKN-6, HKN-7 and HKN-8)].

October 1985 in “PubMed”

research MULTIPLE DEFECTS OF THE HAIR SHAFT IN NETHERTON'S DISEASE.

58 citations , November 1969 in “British Journal of Dermatology”

Netherton's disease causes multiple hair defects.

research Aromatic C-nitrosation of a bioactive molecule. Nitrosation of minoxidil

8 citations , January 2011 in “Organic and Biomolecular Chemistry”

Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.

$Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]$

research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt₂Cl₄(NH₃)₂{μ-HN=C(O)Bu^t}₂]

2 citations , November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials”

A new platinum complex was made and studied, which might help fight cancer better.

research Mutation in 5′ upstream region of GCH I gene causes familial dopa-responsive dystonia

7 citations , June 2011 in “Movement Disorders”

A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.

research INVESTIGATION OF THE INFLUENCE OF INJECTION PULSE DURATION ON THE CAPTURE OF ELECTRONS IN A BETATRON

May 1966 in “Zhurnal Tekhnicheskoi Fiziki (U.S.S.R.) For English translation see Sov. Phys. - Tech. Phys. (Engl. Transl.)”

Finasteride can prevent breast cancer progression by blocking progesterone's conversion to a cancer-promoting hormone.

Ultrasound-Assisted Facile Synthesis and Anticancer Evaluation of Novel N-(2-Substituted Phenyl-4-Oxathiazolidine-3-Carbonothioyl) Benzamide

research Ultrasound-Assisted Facile Synthesis and Anticancer Evaluation of Novel N-(2-substituted phenyl-4-oxathiazolidine-3-carbonothioyl) benzamide

November 2018

Researchers made new compounds that could potentially be developed into anticancer drugs.

research 2,5-Diazabicyclo[2.2.1]heptane in medicinal chemistry: a treasure trove of therapeutic opportunities

January 2026 in “RSC Medicinal Chemistry”

2,5-DBH shows promise for improving drugs in cancer, brain disorders, and infections.

research Wool Fibres: Sectioning and Staining, Differentiation of Ortho and Paracortex

18 citations , January 1965 in “Stain Technology”

research Structural characterization and dissolution profile of mycophenolic acid cocrystals

20 citations , February 2017 in “European journal of pharmaceutical sciences”

The MPA-ISO cocrystal improved solubility and dissolution rate, while the others did not.

research An evaluation of the RapidHIT™ ID system for hair roots stained with Diamond™ Nucleic Acid Dye

December 2023 in “Forensic science international. Genetics”

The RapidHIT ID system can effectively get DNA profiles from hair roots with enough cells.

research Binary and ternary inclusion complexes of finasteride in HPβCD and polymers: Preparation and characterization

37 citations , February 2009 in “Bioorganic & Medicinal Chemistry”

Finasteride complexes with HPβCD and polymers improve solubility, potentially enhancing hair loss treatment.

research Expression of Keratin 75 (K6hf) in Oral Squamous Cell Carcinoma

2 citations , January 2011 in “Dental Medicine Research”

Keratin 75 might be important in oral cancer progression.

research SUPEROXIDE DISMUTASE LOADED NIOSOMES DELIVERY TO HAIR FOLLICLES: PERMEATION THROUGH SYNTHETIC MEMBRANE AND GUINEA PIG SKIN

2 citations , August 2019 in “International Journal of Applied Pharmaceutics”

Niosomes can effectively deliver Superoxide Dismutase to hair follicles, potentially helping prevent hair loss.

research CHROMALENS PRECISION MAPPING AS AN INNOVATIVE SYSTEM FOR MICROZONAL HAIR ANALYSIS: STRUCTURE, ALGORITHM, AND COMPARISON WITH CLASSICAL COLORING TECHNIQUES

December 2023 in “Modern engineering and innovative technologies”

research Medicinal Chemistry of Drugs with N-Oxide Functionalities

54 citations , March 2024 in “Journal of Medicinal Chemistry”

N-oxides are important in medicine for improving drug properties and targeting.

Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Untested Compounds

research Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Nontested Compounds

6 citations , August 2004 in “Journal of Chemical Information and Computer Sciences”

The research found a link between certain molecular features and the biological activity of BC3, which can help identify or create new active compounds.

research Mutation in human hair keratin hHb6 in monilethrix: clinical variation is not due to genetic variation.

September 1997 in “Clinical and Experimental Dermatology”

Indole Glycosides from Calanthe Discolor with Proliferative Activity on Human Hair Follicle Dermal Papilla Cells

research Indole Glycosides from <i>Calanthe discolor</i> with Proliferative Activity on Human Hair Follicle Dermal Papilla Cells

3 citations , April 2021 in “Chemical & Pharmaceutical Bulletin”

Extracts from the Calanthe discolor plant promote hair follicle growth and increase growth factor levels.

research Identification of Novel Mutations in Basic Hair Keratins hHb1 and hHb6 in Monilethrix: Implications for Protein Structure and Clinical Phenotype

62 citations , October 1999 in “Journal of Investigative Dermatology”

New mutations in hair keratin genes can change hair structure and cause monilethrix, with nail issues more common in certain gene mutations.

research Recyclable PolymerizableDeep Eutectic Solvent-BasedThree-Dimensional-Printed Dissolving Microneedles with pH-ResponsiveDelivery of ZIF-8-Loaded Minoxidil for Hair Loss Therapy

March 2026 in “Figshare”

The new microneedle system effectively delivers minoxidil for hair regrowth with minimal side effects.

research SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation

April 2026 in “Cellular and Molecular Immunology”

SPT6 prevents excessive skin inflammation by blocking a feedback loop.

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