117 citations
,
November 2008 in “Drug Development and Industrial Pharmacy” Microemulsions can effectively deliver drugs through the skin but require careful ingredient selection to avoid irritation.
34 citations
,
September 1985 in “Contact Dermatitis” Minoxidil can cause skin irritation like eczema and rash in some users.
6 citations
,
June 2013 in “Toxicological Research” Topical Valproate is safe for human skin and unlikely to cause irritation.
14 citations
,
March 2019 in “European journal of pharmaceutics and biopharmaceutics” Proretinal nanoparticles improve skin absorption and reduce irritation of topical retinoids.
1 citations
,
May 2018 in “International Journal of Advanced Community Medicine” The cream effectively treats acne without causing irritation.
1 citations
,
April 2010 in “Cancer Research” WYE-130600 may cause skin thickening and irritation.
November 2021 in “Egyptian Journal of Medical Microbiology” COVID-19 protective measures led to skin irritation, hair loss, and brittle nails; using skin-friendly products and a healthy diet is recommended.
December 2012 in “SWU eJournals System (Srinakharinwirot University)” Chemical hair removal can cause skin irritation and other issues, but natural alternatives are being explored.
1 citations
,
March 2004 in “Patty's Toxicology” These chemicals can be toxic and cause health issues like irritation, liver damage, and cancer.
42 citations
,
August 2016 in “Nanomedicine” The new adapalene formulation using TyroSpheres is more effective and less irritating for acne treatment.
4 citations
,
November 2012 in “Dermatitis” A man got severe skin irritation after using marking nut sap for hair loss.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Aloe vera improves hair health but may cause irritation for some people.
May 2024 in “Journal of biomaterials science. Polymer ed.” The three-layer microneedle system effectively delivers minoxidil into the skin, showing potential as a safe and efficient treatment for hair loss.
51 citations
,
January 2014 in “International journal of trichology” Shampoo pH can affect hair health, with alkaline shampoos potentially causing damage and acidic shampoos reducing frizz.
2 citations
,
January 2018 in “International Journal of Advanced Community Medicine” The cream effectively reduces hyperpigmentation and signs of aging without causing skin irritation.
December 2023 in “Pharmaceutics” The new adhesive nanoparticles are effective for delivering Minoxidil to the scalp without skin irritation.
Ajwain seed extract improved skin healing and hair growth in a mouse skin irritation model.
Cosmetics can help with mild skin problems and daily care but must be used carefully to avoid skin irritation.
January 2026 in “International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences” The herbal hair serum is safe, non-irritating, and effectively improves hair shine, reduces frizz, and strengthens hair.
5 citations
,
January 2015 in “Skin appendage disorders” Colored hair-thickening fibers can help hide hair loss in some people with Epidermolysis Bullosa but may cause scalp irritation.
October 2018 in “Springer eBooks” The document concludes that various topical medications are effective for skin conditions but often cause skin irritation as a side effect.
9 citations
,
March 2022 in “Journal of radiation research” Boron neutron capture therapy for head and neck cancer can cause side effects like mouth sores and skin irritation, which vary depending on where the treatment is aimed.
8 citations
,
October 2020 in “Pharmaceutics” Dutasteride-loaded nanoparticles coated with Lauric Acid-Chitosan show promise for treating hair loss due to their controlled release, low toxicity, and potential to stimulate hair growth.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The pomegranate leaf extract face cream is stable, non-irritating, and has strong antioxidant and anti-aging effects.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The pomegranate leaf extract face cream is stable, non-irritating, and has strong antioxidant and anti-aging effects.
10 citations
,
June 2018 in “Aaps Pharmscitech” The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
1 citations
,
March 2004 in “Patty's Toxicology” These chemicals can be toxic, causing health issues like cancer, liver damage, and irritation.
July 2023 in “International journal of dermatology, venereology and leprosy sciences” Micro needling is a skin treatment that helps with various skin conditions including stretch marks, by boosting collagen production, but it may cause redness and irritation.
11 citations
,
January 2023 in “BioMed Research International” Microbial biosurfactants could be a safer and environmentally friendly alternative to chemical surfactants in cosmetics.
February 2026 in “Dermatology Reports” Rosemary extract may help hair growth with fewer side effects than conventional treatments.