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Two new enzymes, PAD-R11 and PAD-R4, were cloned and showed activity, with PAD-R11 resembling epidermal enzymes.

TRPS1 is crucial for bone, kidney, and hair follicle development.

A mutation in the hHb3 gene is linked to the hair disorder monilethrix.

Mutations in the POC1A gene can cause a unique form of extreme insulin resistance and short stature.

Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.

A mutation in the hairless gene speeds up severe itchy skin in mice on a special diet.

Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.

Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.

Anti-SRP myopathy can be linked to systemic lupus erythematosus and may improve with specific treatment.

Scientists found new, better-working inhibitors for a hormone-related enzyme.

Certain genes in Iranian sheep are linked to wool production and heat adaptation.

CTHRC1 is essential for healing and preventing heart rupture after a heart attack.

Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.

Red light exposure slows aging in mice by improving fat metabolism.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

LLPS is crucial for RALF signaling, aiding plant growth and stress resilience.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Researchers found a new mutation in the LIPH gene of a woman with a rare hair condition.

A new genetic mutation in mice causes permanent hair loss and skin wrinkling.

Early genetic testing and JAK inhibitors can help treat systemic inflammation in SAVI patients.

PRMT5 inhibitors effectively fight adenoid cystic carcinoma in salivary glands.

Different keratins have unique expression patterns in mouse skin cells.

AtVPS29 is essential for proper plant growth by regulating gibberellin signaling.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

SQSTM1 gene issues may increase the risk of alopecia areata.

The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

Acne patients have higher skin mTORC1 activity, which is reduced by isotretinoin treatment.