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Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.

Gut microbes significantly affect brain steroid levels.

Allopregnanolone helps control oxytocin levels during pregnancy to prevent preterm labor.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Allopregnanolone may enhance alcohol's effects on dopamine neurons, influencing addiction risk.

Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.

In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.

Lower allopregnanolone levels increase stress-related dopamine release in the brain.

Allopregnanolone may help prevent nicotine withdrawal symptoms.

Neurosteroids help protect fetal brains from asphyxia damage.

Changing Allopregnanolone levels in newborns affects adult behavior and anxiety.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Targeting neurosteroids may help prevent drug relapse.

Allopregnanolone and opioids together reduce stress hormone responses during pregnancy.

Allopregnanolone changes gene expression in glioblastoma cells.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Neonatal neurosteroid levels affect adult brain function and behavior.

Allopregnanolone may help reduce inflammation and symptoms related to post-finasteride syndrome.

Neurosteroids affect prolactin levels in sheep differently depending on stress and pregnancy conditions.

Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.

Adjusting neurosteroid levels may help reduce alcohol withdrawal symptoms.

Progesterone and allopregnanolone increase glycine release in rat brain cells.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Neurosteroids like allopregnanolone help control cell death and growth in the developing fetal brain.

Neonatal allopregnanolone and stress affect behavior differently in adolescence and adulthood.

Hormonal contraceptives may reduce social behavior and sexual motivation by lowering allopregnanolone levels.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.