May 2002 in “British Journal of Dermatology” Hair loss caused by longer latent hair cycle and sudden miniaturization, not gradual follicle size reduction.
4 citations
,
September 2021 in “Frontiers in allergy” The conclusion is that understanding the complex relationship between allergies, autoimmunity, and psychological factors is key to treating skin disorders with itching.
3 citations
,
April 2019 in “Journal of Dermatological Treatment” Caffeine shows promise for treating some types of hair loss, but more research is needed.
March 2021 in “Revista Medicina Cutánea Ibero-Latino-Americana” Trichoscopy helps diagnose scarring alopecia early and non-invasively.
January 2018 in “Skin appendage disorders” The document focused on hair disorders, especially alopecia, and discussed treatments and impacts on quality of life.
December 2025 in “Saudi Pharmaceutical Journal” The new minoxidil formula speeds up hair growth effectively.
349 citations
,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
339 citations
,
February 2014 in “Journal of The American Academy of Dermatology” Most patients with frontal fibrosing alopecia are postmenopausal women, and treatments like finasteride and dutasteride can improve or stabilize the condition.
205 citations
,
July 2009 in “Journal of Dermatological Science” Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
165 citations
,
January 2014 in “Dermatology Research and Practice” Zinc is effective for treating various skin conditions, including warts and acne.
127 citations
,
January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
124 citations
,
October 2019 in “Frontiers in Immunology” Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
116 citations
,
February 2017 in “Journal of the American Academy of Dermatology” JAK inhibitors help with skin conditions but need more research on dosing and safety.
114 citations
,
December 1951 in “Archives of Dermatology” Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.
111 citations
,
March 2012 in “Expert Opinion on Drug Delivery” Liposomes could improve how skin care products work but are costly and not very stable.
101 citations
,
July 2020 in “Dermatologic therapy” COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.
98 citations
,
December 2008 in “Journal of Investigative Dermatology” Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
96 citations
,
January 1997 in “Clinics in Dermatology” Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.
87 citations
,
January 2017 in “PLoS Genetics” Removing both KLK5 and KLK7 proteins can prevent death and skin issues in Netherton syndrome.
75 citations
,
August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
71 citations
,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
67 citations
,
September 2003 in “Journal of cutaneous pathology” Skin problems are very common in people with end-stage kidney disease.
66 citations
,
June 2018 in “British Journal of Dermatology” European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.
65 citations
,
April 2021 in “Natural Products and Bioprospecting” Dendrobium plants have compounds useful for treating skin issues and developing new drugs and cosmetics.
63 citations
,
April 2018 in “Journal of the American Academy of Dermatology” Topical JAK inhibitors may help treat some skin conditions but need more research.
55 citations
,
October 2019 in “Dermatology and therapy” Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.
55 citations
,
November 2004 in “Expert opinion on drug safety” Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.
53 citations
,
January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
49 citations
,
May 2018 in “Journal of the American Academy of Dermatology” Applying 2% tofacitinib cream helped some children with severe hair loss grow back hair.
49 citations
,
April 2000 in “Journal of The American Academy of Dermatology” Despite progress in treatment, the exact cause of Alopecia areata is still unknown.