Search

for
Search:

Sort by

Research

120-150 / 1000+ results

research Gene expression profiling suggests severe, extensive central centrifugal cicatricial alopecia may be both clinically and biologically distinct from limited disease subtypes

11 citations , January 2022 in “Experimental Dermatology”

Severe CCCA may be biologically and clinically different from milder forms.

research 284 Deciphering the pathogenesis of central centrifugal cicatricial alopecia

September 2019 in “Journal of Investigative Dermatology”

CCCA in women of African ancestry may be caused by PADI3 gene mutations and intense hair grooming.

research Krtap16, Characterization of a New Hair Keratin-associated Protein (KAP) Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13

47 citations , September 2004 in “Journal of Biological Chemistry”

Hoxc13 regulates specific hair protein genes on mouse chromosome 16.

research 011 Central Centrifugal Cicatricial Alopecia (CCCA) Under the Scope: Histological Similarities between CCCA and Lichen Planopilaris

September 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

CCCA and lichen planopilaris have similar histological features, making them hard to distinguish.

research Against the Rules: Human Keratin K80

40 citations , September 2010 in “Journal of Biological Chemistry”

Keratin K80 is an ancient protein found in various tissues, important for cell structure and tissue differentiation.

research Faculty Opinions recommendation of The Venus flytrap trigger hair-specific potassium channel KDM1 can reestablish the K+ gradient required for hapto-electric signaling.

December 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

The KDM1 gene helps Venus flytraps close by managing potassium ions.

research Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins

13 citations , January 2018 in “Advances in experimental medicine and biology”

Protein Kinase C Epsilon, Which Is Linked to Ultraviolet Radiation-Induced Development of Squamous Cell Carcinomas, Stimulates Rapid Turnover of Adult Hair Follicle Stem Cells

research Protein Kinase Cε, Which Is Linked to Ultraviolet Radiation-Induced Development of Squamous Cell Carcinomas, Stimulates Rapid Turnover of Adult Hair Follicle Stem Cells

10 citations , January 2013 in “Journal of skin cancer”

PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

research AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma

60 citations , October 2020 in “Nature Communications”

AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.

research Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells

80 citations , June 2002 in “Molecular Biology of the Cell”

Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.

research The changes in the expression levels of follicular markers in keratoacanthoma depend on the stage: keratoacanthoma is a follicular neoplasm exhibiting infundibular/isthmic differentiation without expression of CK15

28 citations , February 2014 in “Journal of Cutaneous Pathology”

Keratoacanthoma changes as it grows, showing different hair follicle characteristics at each stage.

research Cytokeratin 15 expression in central, centrifugal, cicatricial alopecia: new observations in normal and diseased hair follicles

14 citations , January 2011 in “Journal of Cutaneous Pathology”

CK15 is not a reliable marker for stem cells in damaged hair follicles from patients with CCCA.

research Corneal epithelial‐like transdifferentiation of hair follicle stem cells is mediated by pax6 and β‐catenin/Lef‐1

20 citations , April 2009 in “Cell Biology International”

Hair follicle stem cells can become corneal-like cells with the help of pax6.

research Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood

33 citations , June 2007 in “Gene Expression Patterns”

CTIP2 may help in skin development and maintenance.

research Studies on basal cell carcinoma with emphasis on the role of the human homologue of the Drosophila patched gene

November 1997 in “Open Archive (Karolinska Institutet)”

PTCH gene mutations contribute to basal cell carcinoma development.

research Polycomb repressive complex 2 in adult hair follicle stem cells is dispensable for hair regeneration

6 citations , December 2021 in “PLoS Genetics”

Polycomb Repressive Complex 2 is not needed for hair regeneration.

research IMMUNOHISTOCHEMICAL EXPRESSION OF KERATIN PROTEINS IN KERATOACANTHOMAS OF THE SKIN

2 citations , March 1994 in “Oncology Reports”

Keratoacanthomas and squamous cell carcinomas have similar keratin patterns, making them hard to tell apart.

research Concerted gene duplications in the two keratin gene families

53 citations , May 1988 in “Journal of Molecular Evolution”

research Pmg-1 and Pmg-2 constitute a novel family of KAP genes differentially expressed during skin and mammary gland development

22 citations , August 1999 in “Mechanisms of Development”

Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.

research A family of type I keratin genes and the homeobox-2 gene complex are closely linked to the rex locus on mouse chromosome 11

49 citations , October 1989 in “Genomics”

Type I keratin genes are closely linked to the rex locus on mouse chromosome 11, affecting hair development.

research Mutation detection of type II hair cortex keratin gene KRT86 in a Chinese Han family with congenital monilethrix

4 citations , August 2013 in “Chinese Medical Journal”

A specific gene mutation in KRT86 is linked to hair disorder in a Chinese Han family.

research A novel point mutation of keratin 17 (KRT17) in a Japanese family with pachyonychia congenita type 2: an RNA-based genetic analysis using a single hair bulb

5 citations , June 2008 in “British Journal of Dermatology”

research LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants

July 2025 in “Journal of Investigative Dermatology”

TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.

research Single nucleotide polymorphisms in the KRT82 promoter region modulate irregular thickening and patchiness in the dorsal skin of New Zealand rabbits

2 citations , May 2024 in “BMC Genomics”

Certain genetic changes in the KRT82 gene may cause patchy skin in New Zealand rabbits.

research Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice.

79 citations , October 2003 in “PubMed”

Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.

research A second KRT71 allele in curly coated dogs

13 citations , November 2018 in “Animal Genetics”

A new gene variant causes curly coats in some dog breeds.

research Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis

14 citations , March 2015 in “Stem Cell Research & Therapy”

ABCG2 protein marks stem-like skin cells in human epidermis.

research A Small Deletion Hotspot in the Type II Keratin GenemK6irs1/Krt2-6gon Mouse Chromosome 15, a Candidate for Causing the Wavy Hair of the Caracul (Ca) Mutation

53 citations , October 2003 in “Genetics”

The mK6irs1/Krt2-6g gene likely causes wavy hair in mice.

research ACE2 Inhibits Dermal Regeneration Through Ang II in Tissue Expansion

1 citations , January 2025 in “Journal of Cosmetic Dermatology”

Inhibiting ACE2 improves skin regeneration during tissue expansion.

research 085 Post-translational regulation of hair keratins in transfected COS-1 cells

July 1995 in “Journal of Dermatological Science”

← Previous page Next page →