3 citations
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April 2011 in “Expert Review of Dermatology” Male hair loss is caused by inactive hair follicle stem cells.
36 citations
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August 2022 in “Frontiers in Cell and Developmental Biology” Sebaceous glands age due to genetic and environmental factors, affecting sebum production and composition.
9 citations
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July 2017 in “Dermatologic Therapy” Two elderly men developed scalp inflammation after using a gel for skin lesions, which healed with treatment except for some permanent hair loss.
186 citations
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February 1980 in “Clinical Endocrinology” During puberty, hormone levels rise, with early increases in some steroids and most menstrual cycles becoming regular by six years after menarche.
5 citations
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March 2019 in “Experimental dermatology” Activating TLR3 may help produce retinoic acid, important for tissue regeneration.
The document concludes that current treatments for androgenic alopecia are not fully effective, but new therapies like botulinum toxin and PRP show promise, and future gene therapy could be beneficial.
June 2020 in “Journal of Investigative Dermatology” Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
7 citations
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January 1971 in “Archives of Dermatological Research” 24 citations
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January 1985 in “Dermatology” Higher levels of certain immune cells in hair follicles may contribute to alopecia areata.
11 citations
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June 2017 in “Asian-Australasian journal of animal sciences” Fox genes are important for hair growth and development in cashmere goats.
December 2022 in “Small methods” A new hair loss treatment using dissolving microneedles was found to speed up hair growth and was more effective than daily use of common hair growth drugs.
KY19382 helps to regrow hair and create new hair follicles.
April 2016 in “Journal of Investigative Dermatology” Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.
June 2023 in “International Journal of Dermatology”
February 2013 in “Journal of the American Academy of Dermatology” Certain gene variations may increase the risk of alopecia, and platelet-rich plasma treatment can improve hair density in those with hair loss; a rare case of facial Becker's nevus was linked to uneven beard growth.
February 2022 in “Authorea (Authorea)” PAON shows skin patterns due to genetic mosaicism.
April 2019 in “Journal of Investigative Dermatology” Increasing COX-2 in mouse skin causes bigger sebaceous glands and thinner hair, but stopping COX-2 can reverse hair thinning.
7 citations
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December 2016 in “Journal of the American Academy of Dermatology” NKG2D+CD4+ T cells are higher in alopecia areata patients and may be involved in the disease.
61 citations
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September 2010 in “Genomics” The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
28 citations
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June 2000 in “PubMed” Androgenetic alopecia is common hair loss due to genetics and DHT.
GHK-Cu and propolis may help prevent scalp aging and hair loss.
9 citations
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June 1959 in “Archives of dermatology” Hair can darken after inflammation and then return to its original color.
January 2019 in “Advances in stem cells and their niches” Krox20 is important for cell differentiation in the brain and hair follicles.
12 citations
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August 2002 in “Archives of Dermatology” January 2003 in “Jiefangjun yixue zazhi” Growth factors in skin increase with age, aiding development and healing.
8 citations
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September 2020 in “Genes & Genomics” 18 citations
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November 2005 in “Archives of Dermatological Research” 60 citations
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December 1988 in “Journal of Biochemical Toxicology” TCDD reduces EGF receptors in the liver, affecting growth and development.
152 citations
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December 2003 in “Micron” As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.
January 1999 in “Journal of S C C J” Certain growth factors regulate hair growth cycles, male hormones affect hair cycles, and drugs like Minoxidil and Finasteride can stimulate hair growth and inhibit male pattern baldness respectively.