38 citations
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January 2014 in “Journal of Dermatological Science” Krtap11-1 is important for hair strength and structure.
36 citations
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December 1991 in “Journal of Dermatological Science” Human nails contain both skin and hair keratins, each needing different extraction methods.
35 citations
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June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
32 citations
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November 1998 in “Journal of Biological Chemistry” Mouse and human keratin 16 can both form filaments, with differences likely due to the tail domain, not the helical domain.
30 citations
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March 2017 in “ACS biomaterials science & engineering” Hair follicles are valuable for regenerative medicine and wound healing.
28 citations
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September 2013 in “European Journal of Histochemistry” Keratins in Malayan pangolins vary by region, suggesting scales evolved from the tail towards the head.
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October 2005 in “PubMed” Keratin 19 expression in certain skin cells is temporary and not a reliable stem cell marker.
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May 1994 in “Journal of Investigative Dermatology” Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
23 citations
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January 1981 Hair is mostly made of three protein types: helical, high-sulfur, and high-tyrosine.
22 citations
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January 2006 in “Journal of Structural Biology” Hair follicles form hard α-keratin filaments in four steps, showing structural differences.
21 citations
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January 1995 in “Molecular Biology Reports” Scientists discovered two versions of a new human hair keratin gene.
18 citations
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December 2010 in “Journal of analytical atomic spectrometry” A new method accurately measures lead levels in hair to assess exposure.
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November 2005 in “European Journal of Cell Biology” Keratin gene clusters in humans and marsupials are similarly organized.
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January 2018 in “Advances in experimental medicine and biology”
16 citations
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July 2016 in “Veterinary Dermatology” Dermoscopy is useful for diagnosing hair loss patterns in dogs.
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January 2018 in “Advances in experimental medicine and biology” Keratin proteins are crucial for hair growth and structure.
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July 2004 in “Journal of morphology” Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
14 citations
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October 2006 in “Journal of Investigative Dermatology” The keratin naming system was updated to include 54 genes, especially for hair-related keratins.
14 citations
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July 1994 in “Journal of Dermatological Science” Keratin mutations may cause scarring alopecia by damaging hair structure.
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July 1994 in “PubMed” Keratins K6 and K16 are expressed more freely in regenerating mouse skin than K1 and K10.
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September 2018 in “Naturwissenschaften” Melatonin treatment increases a specific RNA in goat cells that boosts cashmere growth.
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October 2015 in “Journal of bioactive and compatible polymers” Keratin hydrogel from human hair is a promising biocompatible material for soft tissue fillers.
12 citations
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October 2007 in “PubMed” Keratin helps protect and strengthen hair, reducing damage and color fading.
12 citations
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December 2011 in “Journal of Dermatological Science” The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.
10 citations
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May 2020 in “Journal of proteome research” Explosions don't stop hair proteins from being used to identify people.
9 citations
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September 2019 in “PLoS ONE” K42 and K124 keratins are only found in horse hoof lamellae.
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April 2019 in “Molecules” Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.
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January 1989 in “Sen'i Gakkaishi” Wool and hair fibers absorb moisture similarly due to their keratin structure, with the amount of non-crystalline areas affecting the moisture uptake.
8 citations
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May 2020 in “International journal of biological macromolecules” Certain treatments can increase protein binding to natural hair but are less effective on permed hair.
8 citations
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April 2017 in “Journal of The Royal Society Interface” Giant axonal neuropathy changes the structure of keratin in human hair.