191 citations
,
November 1959 in “Annals of the New York Academy of Sciences” Hair and wool have complex microscopic structures with microfibrils and varying cystine content.
176 citations
,
August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
99 citations
,
January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
98 citations
,
May 2016 in “Genes” Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.
92 citations
,
September 2019 in “ACS nano” A wearable device using electric stimulation can significantly improve hair growth.
89 citations
,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
77 citations
,
March 2000 in “Journal of Investigative Dermatology” The research identified six functional hair keratin genes and four pseudogenes, providing insights into hair formation and gene organization.
75 citations
,
April 2000 in “Developmental Dynamics” Whn is essential for hair growth, and its malfunction causes hair loss.
70 citations
,
February 2007 in “Journal of Investigative Dermatology” K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.
50 citations
,
April 2019 in “Journal of Biosciences” 29 citations
,
September 2017 in “Genes” Selecting specific KRTAP26-1 gene variants can improve wool quality in sheep.
28 citations
,
December 1997 in “Journal of Biological Chemistry” A genetic mutation in the hHa1 gene creates a smaller, but still functional, hair protein without causing hair problems.
22 citations
,
January 1990
19 citations
,
January 2009 in “International review of cell and molecular biology” Hair's strength and flexibility come from its protein structure and molecular interactions.
19 citations
,
September 2014 in “British Journal of Dermatology” Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.
19 citations
,
July 1994 in “Journal of Dermatological Science” Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.
13 citations
,
January 2018 in “Advances in experimental medicine and biology”
12 citations
,
July 2016 in “Forensic science international” The research found that postmortem root bands in hair are likely caused by the breakdown of a specific part of the hair's inner structure after death.
11 citations
,
March 2001 in “Clinics in Dermatology” Hair microscopy is useful for diagnosing hair disorders, but clear definitions are needed for accurate genetic analysis.
10 citations
,
January 1989 in “Archives of Dermatological Research” The method effectively analyzes human hair proteins, especially nonfilamentous ones.
9 citations
,
February 2016 in “Anatomical Science International” Hair proteins change location and structure as hair cells mature.
7 citations
,
June 2021 in “JAAD Case Reports” A woman had hair loss, nail changes, and skin peeling after a COVID-19 infection, which got better on their own.
7 citations
,
January 2017 in “Sub-cellular biochemistry/Subcellular biochemistry”
6 citations
,
November 2021 in “Frontiers in immunology” STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
4 citations
,
January 2015 in “Journal of microbial & biochemical technology” Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
3 citations
,
September 2018 in “Journal of Structural Biology” Oxidized trichocyte keratin has a helical dislocation in its structure.
2 citations
,
May 2022 in “International Journal of Trichology” Brazilian Keratin Treatment can cause skin reactions like redness and scaling, possibly due to formaldehyde.
2 citations
,
February 2021 in “FEBS open bio” Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
January 2024 in “Molecules (Basel. Online)” Juglone from walnut extracts may help repair damaged hair.
January 2013 in “Sen'i Gakkaishi” Microfibrils are key for permanent waves, and hydrolyzed keratin improves wave formation and hair condition.