90 citations
,
August 2004 in “Physiological Genomics” Dermal papilla cells help skin stem cells grow into hair.
87 citations
,
February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
86 citations
,
April 2009 in “Journal of anatomy” Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
78 citations
,
October 2007 in “Journal of Investigative Dermatology” Delta1 is crucial for controlling skin cell growth and preventing tumors in mice.
63 citations
,
April 2005 in “Mechanisms of development” Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.
61 citations
,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
55 citations
,
February 2013 in “The Anatomical Record” Mouse nails are similar to human nails, making them useful for studying nail diseases.
54 citations
,
November 1986 in “Journal of the American Academy of Dermatology” Generalized trichoepitheliomas with hair loss may indicate myasthenia gravis.
26 citations
,
January 2022 The skin is essential for protection, temperature control, and immune defense.
23 citations
,
March 2023 in “eLife” Stem cell differentiation involves gradual chromatin changes and dynamic gene activity.
20 citations
,
February 1994 in “In vitro cellular & developmental biology. Animal” Wool follicles can grow in a lab with the right nutrients and conditions.
13 citations
,
July 2019 in “PLoS ONE” Deleting podoplanin in mice promotes hair growth by enhancing cell migration.
12 citations
,
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Laminin 332 is essential for normal skin cell behavior and structure.
11 citations
,
January 2010 in “Dermatology Research and Practice” Desmosomes are crucial for human skin development, increasing in density as the skin matures.
10 citations
,
August 2021 in “Frontiers in cell and developmental biology” Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.
7 citations
,
June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
7 citations
,
January 2016 in “Methods in molecular biology” Neurons from hair follicles can help repair damaged nerves.
6 citations
,
July 2022 in “World journal of stem cells” Using extracellular vesicles from stem cells can help hair grow by affecting scalp cells and hair follicles.
6 citations
,
October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
4 citations
,
January 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.
4 citations
,
January 2021 in “Cell transplantation” Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
4 citations
,
January 2013 in “Stem cell discovery” Researchers created a cell line from a hair follicle to study hair loss.
3 citations
,
October 2022 in “Frontiers in Surgery” Proteomics combined with other technologies can lead to a better understanding of skin diseases.
3 citations
,
February 2015 in “Mechanisms of development” Hormones and stretching both needed for nipple area skin growth in mice.
2 citations
,
September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
1 citations
,
February 2023 in “International Journal of Molecular Sciences” The fascial layer is a promising new target for wound healing treatments using biomaterials.
1 citations
,
January 2012 in “International journal of trichology” Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hidradenitis suppurativa tunnels have different microenvironments, suggesting targeted treatments could be more effective.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hidradenitis suppurativa tunnels have different microenvironments, suggesting targeted treatments could be more effective.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hidradenitis suppurativa tunnels have different microenvironments, suggesting targeted treatments could be more effective.