research Proteomics as a tool to improve novel insights into skin diseases: what we know and where we should be going
Proteomics combined with other technologies can lead to a better understanding of skin diseases.
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research A Homozygous Missense Variant in K25 Underlying Overlapping Phenotype with Woolly Hair and Dental Anomalies
A specific mutation in the K25 gene causes a rare genetic disorder with curly hair at birth and later hair loss, along with dental issues.
research Discreet monilethrix: De novo mutation on the example of polish families
A new mutation caused a rare hair disorder in a Polish girl, not inherited from her family.
research Colourless side of the nude mutation: Foxn1 and hair pigmentation
Foxn1 is essential for hair pigmentation by directing pigment transfer to hair cells.
research Lipid signaling in keratinocytes: Lipin-1 plays a PArt
Lipin-1 is important for skin cell differentiation and skin barrier function.
research Receptor tyrosine kinase Kit action in skin melanocytes: is it exclusively cell autonomous?
KIT's role in skin cells is not entirely independent, as other cells can influence its function.
research Integrated Meta-Analysis of Scalp Transcriptomics and Serum Proteomics Defines Alopecia Areata Subtypes and Core Disease Pathways
Early intervention in patch-type alopecia may prevent progression to more severe forms by targeting immune pathways and preserving keratin.
research The Utility of De-epithelialization in Subcutaneous Skin Flap Transposition.
De-epithelialization reduces complications in subcutaneous skin flap procedures.
research Erythrocyte Extracellular Vesicles Amalgamate into the Hair and Skin to Maintain Homeostasis
Erythrocyte extracellular vesicles help hair growth and skin health.
research Skin Appendage Proteins of Tetrapods: Building Blocks of Claws, Feathers, Hair and Other Cornified Epithelial Structures
Understanding proteins in skin structures like claws and hair is crucial for future research.
research Spatiotemporal Expression and Haplotypes Identification of KRT84 Gene and Their Association with Wool Traits in Gansu Alpine Fine-Wool Sheep
The KRT84 gene is linked to better wool quality in Gansu Alpine Fine-wool sheep.
research Trends in biopolymer science applied to cosmetics
Biopolymers are increasingly used in cosmetics for their non-toxicity and skin benefits, with future biotech advancements likely to expand their applications.
research 414 A new form of ectodermal dysplasia caused by mutations in TSPEAR
Mutations in the TSPEAR gene cause a new form of ectodermal dysplasia affecting hair and tooth development.
research Notes from the Editor Emeritus
Scalp tools, tracking progress, targeting scalp inflammation, and avoiding certain hair treatments can improve female hair loss treatment.
research Clinical Snippets
Razor bumps are linked to a genetic variant, misoprostol helps erythromelalgia pain, steroid ointments don't affect skin rhythms, and certain antibodies are common in localized scleroderma.
research Comparative Study of Some Potential Paracrine Factors Produced by Normal and Androgenetic Alopecia Hair Follicles
Balding hair follicles have less growth-promoting factors and more inhibitory factors, leading to hair loss.
research Nestin expression in hair follicle sheath progenitor cells
Nestin is found in hair follicle progenitor cells, linking them to neural stem cells.
research Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation
BMP and Wnt signaling balance controls hair follicle stem cell activity and hair growth.
research The structure of people’s hair
Hair's molecular structure is mostly consistent, but genetic differences affect lipid types, which could help diagnose diseases.
research Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone
Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.
research Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin
Dermal papilla cells help skin stem cells grow into hair.
research Role of the Notch Ligand Delta1 in Embryonic and Adult Mouse Epidermis
Delta1 is crucial for controlling skin cell growth and preventing tumors in mice.
research Ichthyosis follicularis, alopecia, and photophobia (IFAP) syndrome
IFAP syndrome is a rare genetic disorder causing skin, hair, and eye issues, with limited treatment options.
research Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions
Spermidine may help reduce hair loss and deserves further testing as a treatment.
research The structure of the cornified claw sheath in the domesticated cat (Felis catus): implications for the claw‐shedding mechanism and the evolution of cornified digital end organs
Cat claws stay sharp by shedding their outer layer through microcracks formed during activities.
research Establishment and characterization of a canine keratinocyte organoid culture system
A new method to study dog skin diseases using lab-grown skin cells was developed.
research Comparative proteomic analyses using iTRAQ-labeling provides insights into fiber diversity in sheep and goats
The research found specific proteins that affect fiber characteristics and hair growth in sheep and goats.
research Novel KRT 83 and KRT 86 mutations associated with monilethrix
New mutations in KRT83 and KRT86 are linked to the hair disorder monilethrix.
research Integrated miRNA-mRNA analysis reveals regulatory pathways underlying the curly fleece trait in Chinese tan sheep
Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.
research Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness
Both gene and non-gene areas of DNA evolved to make some mammals hairless.