research Isolation and characterization of a sheep cysteine-rich cuticle keratin pseudogene
Researchers found a non-functional sheep keratin gene due to mutations.
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research Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity
A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
research Histological evaluation of hair keratin based templates in mice
Keratin sponges are as biocompatible as collagen, but keratin gels are slightly less so.
research Experimental study on the compatibility and degradation of human hair keratin bridging for peripheral nerve defects
Human hair keratin can help nerve regeneration and is a promising material for nerve repair.
research Experiment study of human hair keratin transplanted to adult rat after spinal cord injury
Human hair keratin may help repair spinal cord injuries.
research Effects of chemical structures of polycarboxylic acids on molecular and performance manipulation of hair keratin
A non-toxic formula using polycarboxylic acids strengthens and improves hair.
research Characterizing Wool Keratin
Wool keratin is reactive, biocompatible, biodegradable, and can model keratin from other sources.
research The Intermediate Filament Architecture as Determined by X-Ray Diffraction Modeling of Hard α-Keratin
Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.
research Action of Nucleophilic Reagents on Hair Keratin
Nucleophilic reagents break down hair keratin, forming more lanthionine and lysinoalanine than in wool.
research Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay
Certain genetic variants in keratins increase the risk of tooth decay.
research Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly
The study revealed the detailed structure of a keratin dimer, aiding understanding of how intermediate filament proteins function.
research A Small Deletion Hotspot in the Type II Keratin GenemK6irs1/Krt2-6gon Mouse Chromosome 15, a Candidate for Causing the Wavy Hair of the Caracul (Ca) Mutation
The mK6irs1/Krt2-6g gene likely causes wavy hair in mice.
research Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice
Overexpressing IGF-1 in mice leads to skin abnormalities and tumors.
research Human stratum corneum proteomics reveals cross‐linking of a broad spectrum of proteins in cornified envelopes
A wide range of proteins are integrated into the skin's protective layer.
research Dermo‐epidermal interactions in reptilian scales: Speculations on the evolution of scales, feathers, and hairs
Reptilian scales, feathers, and hairs evolved from changes in skin cell interactions.
research Hair colouring systems delivering colour with reduced fibre damage
Using chelants in hair dye reduces fiber damage by preventing harmful radicals.
research Spiny Keratoderma
Spiny keratoderma is a rare skin condition with small spines on palms and soles, possibly linked to abnormal hair formation.
research Embryonic keratinization in vertebrates in relation to land colonization
Keratinization in embryos helped vertebrates adapt to land by forming a protective skin barrier.
research The walking dead: sequential nuclear and organelle destruction during hair development
Cells in hair die by breaking down their DNA and mitochondria as they form keratin.
research KRT17 promotes endometrial cancer cell migration as well as angiogenesis by regulating HIF-1α/VEGF pathway
KRT17 may be a new target for endometrial cancer treatment because it helps cancer cells move and form new blood vessels.
research 840 Early and late matrix progenitors form the terminally differentiated cell layers of the hair follicle
Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
research The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice
Disrupting the Sox21 gene in mice causes hair loss and regrowth cycles.
research The biology and genetics of curly hair
Curly hair is influenced by specific genetic variations.
research Characterization of sciellin, a precursor to the cornified envelope of human keratinocytes
Sciellin is a protein that helps form protective layers in skin, hair, and nails.
research Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface
Blocking a specific protein signal can make hair grow on mouse nipples.
research The cellular basis of mechanosensory Merkel-cell innervation during development
BMP signaling is essential for the development of touch domes.
research Mechanical stress and the development of pseudo‐comedones and tunnels in Hidradenitis suppurativa/Acne inversa
Mechanical stress may cause lesions in Hidradenitis suppurativa.
research Studies of androgen metabolism and action in cultured hair and skin cells
Androgens don't directly affect hair cell growth or protein production.
research Inherited disorders of the skin in human and mouse: from development to differentiation.
Research on skin disorders in humans and mice has improved understanding of hair and skin development.
research Tretinoin Treatment of Fox-Fordyce Disease
Tretinoin may be effective for treating Fox-Fordyce disease.