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research The structure of the cornified claw sheath in the domesticated cat (Felis catusi>): implications for the claw‐shedding mechanism and the evolution of cornified digital end organs

45 citations , April 2009 in “Journal of anatomy”

Cat claws stay sharp by shedding their outer layer through microcracks formed during activities.

research Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface
41 citations , October 2008 in “The American journal of pathology”

Blocking a specific protein signal can make hair grow on mouse nipples.

research Does collapse of immune privilege in the hair-follicle bulge play a role in the pathogenesis of primary cicatricial alopecia?
39 citations , November 2009 in “Clinical and Experimental Dermatology”

Immune privilege collapse in hair follicles may cause permanent hair loss in certain conditions.

research Ritlecitinib and brepocitinib demonstrate significant improvement in scalp alopecia areata biomarkers
36 citations , December 2021 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.

research Serial sections of atrophic acne scars help in the interpretation of microscopic findings and the selection of good therapeutic modalities
36 citations , November 2011 in “Journal of the European Academy of Dermatology and Venereology”

Effective acne scar treatment should use combination therapy based on specific skin changes.

research Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome
34 citations , July 2020 in “American journal of human genetics”

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.

research Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles
34 citations , June 2008 in “In vitro cellular & developmental biology. Animal”

Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.

research Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology
33 citations , February 2012 in “British Journal of Dermatology”

Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.

research The cellular basis of mechanosensory Merkel-cell innervation during development
32 citations , February 2019 in “eLife”

BMP signaling is essential for the development of touch domes.

research Localization of Merkel cells at hairless and hairy human skin sites using keratin 18
28 citations , September 1995 in “Biochemistry and Cell Biology”

Merkel cells are more densely found in hairless skin areas like palms and soles.

research De novoi> mutations in monilethrix
26 citations , December 2003 in “Experimental Dermatology”

Specific keratin gene mutations can cause monilethrix.

research Progress report on hair keratin research
21 citations , June 2002 in “International Journal of Cosmetic Science”

Advancements in hair keratin research could lead to better hair health treatments.

research Distribution of keratin and associated proteins in the epidermis of monotreme, marsupial, and placental mammals
21 citations , June 2003 in “Journal of Morphology”

Monotreme and marsupial skin proteins show primitive features and species-specific differences compared to placental mammals.

research Investigation of aging effects in human hair using atomic force microscopy
20 citations , July 2010 in “Skin Research and Technology”

Aging makes hair thinner and rougher, with less clear edges.

research Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling
19 citations , September 2019 in “PLOS genetics”

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

research A novel missense mutation in the mouse hairless gene causes irreversible hair loss: Genetic and molecular analyses of Hrm1Enu
18 citations , February 2006 in “Genomics”

A new genetic mutation in mice causes permanent hair loss and skin wrinkling.

research Integrated miRNA-mRNA analysis reveals regulatory pathways underlying the curly fleece trait in Chinese tan sheep
17 citations , May 2018 in “BMC genomics”

Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.

research Diagnosis directs treatment in fungal infections of the skin.
17 citations , October 2015 in “PubMed”

Proper diagnosis is essential for effective treatment of skin fungal infections.

research Cultured nail keratinocytes express hard keratins characteristic of nail and hair in vivo
16 citations , August 1992 in “Archives of dermatological research”

Lab-grown nail cells show characteristics similar to natural nail and hair.

research Isolation of Stem Cells and Progenitors from Mouse Epidermis
13 citations , May 2017 in “Current Protocols in Stem Cell Biology”

A method was developed to isolate and study hair follicle stem cells from mouse skin.

research Isolating Hair Follicle Stem Cells and Epidermal Keratinocytes from Dorsal Mouse Skin
13 citations , April 2016 in “Journal of Visualized Experiments”

The method successfully isolates hair follicle stem cells and skin cells from mice for research.

research Eruptive Vellus Hair Cysts: Report of a New Case with Immunohistochemical Study and Literature Review
13 citations , January 2012 in “Dermatology”

Eruptive vellus hair cysts are rare, benign skin lesions that are hard to treat.

research The in vitro Assembly of Hair Follicle Keratins: Comparison of Cortex and Companion Layer Keratins
13 citations , January 2002 in “Biological chemistry”

Different conditions affect how hair proteins assemble, and certain mutations can change their structure.

research Changes in the Molecular Structure of Hair in Insulin-Dependent Diabetes
13 citations , April 1997 in “Biochemical and Biophysical Research Communications”

Insulin-dependent diabetes alters hair's molecular structure, making it useful for studying diabetes effects.

research Incorporation of Selenium-75 into Dog Hair
13 citations , October 1960 in “Experimental Biology and Medicine”

Selenium-75 stays in dog hair for up to 316 days.

research An analysis of gene expression data involving examination of signaling pathways activation reveals new insights into the mechanism of action of minoxidil topical foam in men with androgenetic alopecia
12 citations , June 2017 in “Cell Cycle”

Minoxidil foam helps hair growth by increasing good proteins and decreasing bad pathways in men with hair loss.

research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
11 citations , March 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.

research Suitability of hair type for dermatophytes perforation and differential diagnosis of T. mentagrophytesi> from T. verrucosumi>
11 citations , January 2016 in “Mycoses”

Human black hair is best for distinguishing between T. mentagrophytes and T. verrucosum.

research Isolation and characterization of genomic clones of human sequences presumably coding for hair cysteine-rich proteins
11 citations , January 1997 in “Journal of Dermatological Science”

A new protein linked to hair strength was identified, aiding in understanding brittle hair conditions.

research Crosslinking structure of keratin. V. Number and type of crosslinks in microstructures of untreated and potassium cyanide treated human hair
11 citations , September 1996 in “Journal of applied polymer science”

Potassium cyanide treatment changes hair's disulfide bonds, making it more elastic.

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Search:

Products matching "keratin i"

Research

research The structure of the cornified claw sheath in the domesticated cat (Felis catusi>): implications for the claw‐shedding mechanism and the evolution of cornified digital end organs

research Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface

research Does collapse of immune privilege in the hair-follicle bulge play a role in the pathogenesis of primary cicatricial alopecia?

research Ritlecitinib and brepocitinib demonstrate significant improvement in scalp alopecia areata biomarkers

research Serial sections of atrophic acne scars help in the interpretation of microscopic findings and the selection of good therapeutic modalities

research Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome

research Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles

research Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology

research The cellular basis of mechanosensory Merkel-cell innervation during development

research Localization of Merkel cells at hairless and hairy human skin sites using keratin 18

research De novoi> mutations in monilethrix

research Progress report on hair keratin research

research Distribution of keratin and associated proteins in the epidermis of monotreme, marsupial, and placental mammals

research Investigation of aging effects in human hair using atomic force microscopy

research Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling

research A novel missense mutation in the mouse hairless gene causes irreversible hair loss: Genetic and molecular analyses of Hrm1Enu

research Integrated miRNA-mRNA analysis reveals regulatory pathways underlying the curly fleece trait in Chinese tan sheep

research Diagnosis directs treatment in fungal infections of the skin.

research Cultured nail keratinocytes express hard keratins characteristic of nail and hair in vivo

research Isolation of Stem Cells and Progenitors from Mouse Epidermis

research Isolating Hair Follicle Stem Cells and Epidermal Keratinocytes from Dorsal Mouse Skin

research Eruptive Vellus Hair Cysts: Report of a New Case with Immunohistochemical Study and Literature Review

research The in vitro Assembly of Hair Follicle Keratins: Comparison of Cortex and Companion Layer Keratins

research Changes in the Molecular Structure of Hair in Insulin-Dependent Diabetes

research Incorporation of Selenium-75 into Dog Hair

research An analysis of gene expression data involving examination of signaling pathways activation reveals new insights into the mechanism of action of minoxidil topical foam in men with androgenetic alopecia

research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes

research Suitability of hair type for dermatophytes perforation and differential diagnosis of T. mentagrophytesi> from T. verrucosumi>

research Isolation and characterization of genomic clones of human sequences presumably coding for hair cysteine-rich proteins

research Crosslinking structure of keratin. V. Number and type of crosslinks in microstructures of untreated and potassium cyanide treated human hair