89 citations
,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
79 citations
,
August 1998 in “The Journal of Cell Biology” Keratin 16 delays skin maturation and affects skin and hair development in mice.
78 citations
,
May 2012 in “Journal of Investigative Dermatology” A specific gene mutation causes woolly hair and hair loss.
51 citations
,
February 2009 in “Journal of dermatological science” Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
50 citations
,
February 2016 in “Journal of Investigative Dermatology” A mutation in the KRT25 gene causes a rare hair disorder with thin, woolly hair.
49 citations
,
March 2004 in “Journal of Investigative Dermatology” The hHa7 gene is regulated by androgens in certain body hair, not scalp hair.
48 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.
43 citations
,
October 2006 in “Journal of Cell Science” Keratin 10 end domains may increase skin cancer risk by reducing cell death.
40 citations
,
November 2021 in “International Journal of Molecular Sciences” Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
36 citations
,
December 1991 in “Journal of Dermatological Science” Human nails contain both skin and hair keratins, each needing different extraction methods.
28 citations
,
December 2011 in “Biocatalysis and biotransformation” PDI helps restore over-bleached hair's strength and structure by attaching special peptides.
25 citations
,
August 2020 in “Experimental eye research/Experimental Eye Research” Different types of cells in the eye express specific keratins at various stages of development.
22 citations
,
January 2020 in “PeerJ” Keratin peptides in hair might help identify gender and ethnicity.
19 citations
,
December 2015 in “Journal of Investigative Dermatology” The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
16 citations
,
April 2021 in “Biomedicines” Ferulic acid helps wounds heal faster by reducing inflammation and promoting skin cell movement.
15 citations
,
January 2018 in “Advances in experimental medicine and biology” Keratin proteins are crucial for hair growth and structure.
15 citations
,
July 2004 in “Journal of morphology” Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
14 citations
,
July 1994 in “Journal of Dermatological Science” Keratin mutations may cause scarring alopecia by damaging hair structure.
7 citations
,
May 2025 in “Journal of Biomedical Science” Keratin 6A increases skin inflammation, suggesting it could be a target for treating certain skin diseases.
7 citations
,
May 2021 in “Applied sciences” Proteins like BSA and keratin can effectively style hair and protect it, offering eco-friendly alternatives to chemical products.
7 citations
,
January 2017 in “Sub-cellular biochemistry/Subcellular biochemistry”
5 citations
,
January 2022 in “Scientific reports” The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
5 citations
,
February 2007 in “Cytology and genetics” Gene expression regulates keratin production for normal hair growth.
2 citations
,
February 2021 in “FEBS open bio” Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
2 citations
,
January 2013 in “Elsevier eBooks” The document explains the genetic causes and characteristics of inherited hair disorders.
1 citations
,
May 2025 in “Scientific Reports” The study identified key genes and pathways that influence goat wool quality and growth.
1 citations
,
February 2013 in “InTech eBooks” Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
December 2025 in “The Journal of Cell Biology” Keratin 15 helps maintain skin cell growth and repair.
June 2025 in “Advances in Clinical and Experimental Medicine” Keratin biomaterials could help heal wounds and regenerate tissue, but more testing is needed.
August 2024 in “Journal of Animal Science and Technology” Angora goat hair growth is influenced by gene expression, sex hormones, and breed differences.